ArticleFrontiers in public health2025
Clinical characteristics of pulmonary embolism at extremely high altitude: a single-center retrospective study.
Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Hemodynamic and Thrombotic Vulnerability in Pulmonary Arterial Hypertension at High Altitude: Multivariable Predictors of Mortality.Medicina (Kaunas, Lithuania) · 2026Article
- Postpartum Venous Thromboembolism: Altitudinal Gradients, Decadal Trends, and PE-Specific Risk Profiling in Highland Populations.Canadian respiratory journal · 2026Article
- Venous thromboembolism at high altitude: mechanisms, risk stratification, and precision prevention.Frontiers in physiology · 2026Review
- High-altitude hyperuricemia: a double-edged sword of adaptation and maladaptation.Frontiers in public health · 2026Article
- High-Altitude Pulmonary Embolism: Epidemiology, Pathophysiology, Diagnosis, and Management.Canadian respiratory journal · 2025Review
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Authors and funding
9 authors.
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Abstract
Background: Exposure to high altitude (HA) has been shown to significantly increase the risk of venous thromboembolism (VTE). However, the clinical characteristics of VTE at extremely high altitudes remain poorly understood. In this single-center retrospective study, we aimed to compare the clinical characteristics and prognoses of pulmonary embolism (PE) patients at extremely high altitudes with those at low altitudes (LA). Methods: This retrospective analysis focused on PE patients treated at the General Hospital of Xinjiang Military Command between November 1, 2019, and November 1, 2022. The high-altitude group (HA-Group) consisted of patients who sought medical treatment after they had fallen ill into the plateau area, and the low-altitude group (LA-Group) consisted of local residents. Results: We identified a total of 17 PE patients in the HA-Group and 62 patients in the LA-Group. The average altitude in the HA-Group was 5,041 ± 85.34 m, and 802.1 ± 11.10 m in the LA-Group ( Conclusion: This retrospective study revealed the clinical characteristics of PE patients at extremely high altitudes. High-altitude exposure may increase the susceptibility of young people to PE, and abnormal serum uric acid metabolism may be a potential risk factor for PE in high altitude areas.
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