ArticleFrontiers in global women's health2025
Maternal outcomes of severe preeclampsia and eclampsia and associated factors among women admitted at referral hospitals of amhara regional state, institutional-based cross-sectional study, North-West Ethiopia.
Article in Frontiers in global women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.
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7 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Diagnostic accuracy of NLR, MLR, PLR, SII, and SIRI for predicting major adverse maternal outcomes in preeclampsia: A systematic review.The Journal of international medical research · 2026Pooled it
- Maternal mortality in Ethiopia (2015-2025): a systematic review of recent evidence and determinants.BMC public health · 2025Pooled it
- Severe maternal outcomes and their underlying causes in Ethiopia. Systematic review and meta-analysis.Women's health (London, England)Pooled it
- Predictors of maternal and perinatal mortality among pregnant women with preeclampsia and eclampsia at Garissa County Referral Hospital: a retrospective cohort study.BMC pregnancy and childbirth · 2026Article
- Posterior Reversible Encephalopathy Syndrome in Eclampsia: A Prospective Study of Risk Factors and Outcomes.Cureus · 2026Article
- Neurocysticercosis mimicking eclampsia in a pregnant woman with a history of preeclampsia: a case report.Frontiers in medicine · 2026Article
- Development and internal validation of a nomogram for predicting adverse pregnancy outcomes in women with early-onset preeclampsia.Frontiers in medicine · 2026Article
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Abstract
Introduction: Severe preeclampsia/eclampsia is a multi-systemic pregnancy condition that manifests after 20 weeks of gestation and is linked to a high global rate of maternal morbidity and mortality. It is responsible for 11%-14% of maternal mortality globally and is the second most frequent direct obstetrical cause of death. This study aimed to assess maternal outcomes of severe preeclampsia/eclampsia and associated factors in mothers admitted to referral hospitals in the Amhara Regional State of North West Ethiopia. Methods: An institutionally based cross-sectional investigation on the outcomes of severe preeclampsia/eclampsia in mothers was carried out from April 1 to September 30, 2018. Using the census sampling technique, 456 study participants were included in the study. Data were coded, verified, and imported into Epi-info version 7.2 before being exported and analyzed in SPSS version 26. To determine the determinants of maternal outcomes of severe preeclampsia or eclampsia, binary logistic regression was employed, with a significance level of 95% confidence interval of odds ratio at Results: Overall, severe preeclampsia and eclampsia were shown to have unfavorable maternal outcomes in 37.7% (95% CI: 32.8%, 42.3%). The following variables had statistically significant associations with unfavorable maternal outcomes of severe preeclampsia and eclampsia: educational status (AOR = 4.5, 95% CI: 1.95, 12.31), residence (AOR = 2.1, 95% CI: 1.17, 3.72), monthly family income (AOR = 2.7, 95% CI: 1.25, 6.12), parity (AOR = 6.7, 95% CI: 1.55, 12.6), history of abortion (AOR = 3.5, 95% CI: 1.63, 7.58), booking status (AOR = 5.8, 95% CI: 3.15, 9.72), and time of drug given (AOR = 4.9, 95% CI: 1.86, 13.22). Conclusion: It was discovered that severe preeclampsia and eclampsia had a high overall rate of unfavorable maternal outcomes. Promoting early antenatal care booking and formal education for women can reduce preeclampsia and eclampsia outcomes.
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