ArticleTaiwan journal of ophthalmology
Results of long-term antiviral prophylactic treatment on the course of herpes zoster ophthalmicus with ocular involvement: A case series in a tertiary uveitis clinic - A 1-year follow-up.
Article in Taiwan journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- How to interpret low-dose valacyclovir for postherpetic neuralgia in the Zoster Eye Disease Study-a randomized clinical trial.Annals of translational medicine · 2026Article
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Authors and funding
4 authors.
Funding
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Abstract
purposeTo study the efficacy of long-term antiviral monotherapy on herpes zoster ophthalmicus (HZO) with eye involvement. MATERIALS AND
methodsThe patients with primary, recurrent, and chronic HZO with at least 1 year of follow-up were included in the study. The primary endpoint of the study was HZO recurrence with ocular presentations.
resultsA total of 17 patients were included in the study. Eleven (64.7%) patients were included in the primary HZO group and 6 (35.3%) patients were included in the recurrent/chronic HZO group. In the primary HZO group, 10 (90.9%) patients responded to antiviral alone. One patient failed antiviral treatment after 7 months and responded to a combination of methotrexate and antiviral therapy. In the recurrent and chronic HZO group, 4 (66.7%) patients responded to isolated antiviral treatment. No systemic side effects were observed during the study period.
conclusionLong-term antiviral monotherapy may be an effective prophylactic treatment in patients with primary, recurrent, persistent HZO to treat the infection and maintain remission; however, this hypothesis should be examined in more potent study with larger population.
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