Evidence map›Paper›PMID 40213275›Full record

ArticleLancet regional health. Americas2025

COVID-19 and its impact on life expectancy among First Nations people in Alberta, Canada from 2019 to 2022: a population-based study.

Chris Sarin, Dean T Eurich, Olivia Weaver, Li Huang, Sydney Rudko, Cerina Dubois, Oacia Fair, Lisa A Wozniak, Bonnie Healy, Lea Bill and 4 more

Abstract read
In one paragraph

Article in Lancet regional health. Americas, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Chris SarinIndigenous Services Canada, Alberta Region, Edmonton, Alberta, Canada.
Dean T EurichSchool of Public Health, University of Alberta, Edmonton, Alberta, Canada.
Olivia WeaverSchool of Public Health, University of Alberta, Edmonton, Alberta, Canada.
Li HuangAlberta Health, Edmonton, Alberta, Canada.
Sydney RudkoAlberta Health, Edmonton, Alberta, Canada.
Cerina DuboisSchool of Public Health, University of Alberta, Edmonton, Alberta, Canada.
Oacia FairSchool of Public Health, University of Alberta, Edmonton, Alberta, Canada.
Lisa A WozniakSchool of Public Health, University of Alberta, Edmonton, Alberta, Canada.
Bonnie HealyBlackfoot Confederacy, Calgary, Alberta, Canada.
Lea BillAlberta First Nations Information Governance Centre, Canada.
Lynden CrowshoeUniversity of Calgary, Alberta, Canada.
Ambikaipakan SenthilselvanSchool of Public Health, University of Alberta, Edmonton, Alberta, Canada.
Amy ColquhounAlberta Health, Edmonton, Alberta, Canada.
Salim SamananiOKAKI Health Intelligence Inc. Calgary, Alberta, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: COVID-19 differentially impacted First Nations people due to pre-existing social, racial, and systemic inequities. This study explores life expectancy of First Nations people and the perspectives of First Nations health staff on the observed trends in life expectancy during the pandemic in Alberta, Canada. Methods: All First Nations people in Alberta from a First Nations-identifying dataset (1999-2022) were included in this descriptive study (n = 164,964 in 2017, 49.7% male, 50.3% female, mean age 29.4 years [standard deviation 1.46; range 26.9-31.9 years]). In partnership with First Nations health managers, knowledge users, and using appropriate methods for First Nations people, we examined how the pandemic affected life expectancy in First Nations vs non-First Nations people. First Nations health managers were asked their opinions on observed trends in mortality during the pandemic through individual conversations. Findings: Since 1999, First Nations people consistently had lower life expectancies compared to non-First Nations. In 2019-2021, life expectancy dropped 7.3 years (70.4 [95% confidence interval (CI) 69.48-71.24] to 63.1 [CI 62.28-64.02]) for First Nations people vs 1.4 years (82.8 [CI 82.65-82.92] to 81.4 [CI 81.22-81.51]) for non-First Nations people. Mortality was highest in young adult First Nations females relative to non-First Nations females (∼11-fold increase) during COVID-19. First Nations people had lower life expectancy across most age categories. The 20-50 year age groups had some of the highest relative mortality rates. Health managers observed similar life expectancy trends, perceiving that the pandemic exacerbated existing issues, including delayed access to care, poisonings (i.e., accidental or intentional overdoses), and pre-existing health conditions. Interpretation: First Nations people in Alberta had a substantial drop in life expectancy during the pandemic compared to non-First Nations people. From the perspective of First Nations health managers, the pandemic indirectly exacerbated existing social and health issues, possibly contributing to the trend in life expectancy. Significant initiatives and resources will need to be deployed to assist First Nations communities to close these gaps. Funding: Canadian Institutes of Health research (#PJT-178219).

Indexed as

All-cause mortalityCoronavirusEpidemiologyFirst NationsPopulation healthPublic health

Identifiers

PMID40213275
PMCPMC11982942

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.