Evidence map›Paper›PMID 40213271›Full record

ArticleComputational and structural biotechnology journal2025

Apico-basal intercalations enable the integrity of curved epithelia.

Samira Anbari, Pedro Gómez-Gálvez, Pablo Vicente-Munuera, Luis M Escudero, Javier Buceta

Abstract read
In one paragraph

Article in Computational and structural biotechnology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Samira AnbariBiomedical Engineering Department, Johns Hopkins University, Baltimore, MD 21205, USA.
Pedro Gómez-GálvezMRC Laboratory of Molecular Biology, Cambridge Biomedical Campus, Francis Crick Ave., Trumpington, Cambridge CB2 0QH, Cambridgeshire, UK.
Pablo Vicente-MunueraLaboratory for Molecular Cell Biology, University College London, London, UK.
Luis M EscuderoInstituto de Biomedicina de Sevilla (IBiS), Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, 41013 Seville, Spain.
Javier BucetaInstitute for Integrative Systems Biology (I2SysBio), Theoretical and Computational Systems Biology Program, CSIC-UV, Paterna 46980, Spain.

Funding

SPERMIDINE DERIVATIVES AS POTENTIAL ANTICANCER AGENTSR01CA022153 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI PORTER, CARL W · 1985 to 2007
$2.6M
NCI NIH HHS R01 CA022153
6 · The paper itself

Abstract

Non-invasive force inference based on imaging data has significantly advanced our understanding of the mechanical cues driving morphogenesis. In 2D studies of confluent tissues, these methods allow for the computation of forces acting on cells by analyzing their geometrical features. Here, we present a novel approach for 3D force and energy inference in curved epithelia. Specifically, we focus on tubular epithelia, which form the foundation of many vital organs, including the lungs, kidneys, and vasculature. Our technique analyzes the average mechanical behavior of cells along their apico-basal axis and is based on an optimal parametrization of a vertex model aimed at obtaining effective tissue parameters. We apply our method to

Identifiers

PMID40213271
PMCPMC11982039

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.