ArticleHealth science reports2025
The Efficacy of Platelet-Rich Plasma in Facial Lichen Planus Pigmentosus: A Prospective Pilot Study.
Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Non-ablative dermal remodeling lasers in acquired dermal macular hyperpigmentation: A scoping review.PloS one · 2026Article
- Platelet-rich therapies in cutaneous and mucocutaneous disorders characterized by inflammatory tissue responses: mechanistic insights and clinical evidence.Frontiers in medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Lichen planus pigmentosus (LPP) is an uncommon variant of lichen planus which most commonly affects middle-aged individuals with skin of color. Despite multiple treatment modalities available for LPP, their efficacies are unpredictable and often disappointing. In this study, we aimed to investigate the use of platelet-rich plasma (PRP) as a novel therapy for LPP. Methods: Twelve patients received three sessions of intradermal PRP injection at a 2-week interval. Week 0, 2 and 4 were treatment sessions, while Week 6, 8 and 12 were follow-up visits. Mean melanin index (MI), physician global assessment (PGA) and clinical photographs were assessed at Week 0, 2, 4, 6, 8, and 12, while quartile grading scale (QGS) and patient satisfaction were evaluated at Week 2, 4, 6, 8, and 12. Adverse effects were also recorded. Results: Initial mean MI was 448.19 (18.76) and declined to 409.64 (19.13) at week 12 ( Conclusion: We report the first pilot study utilizing PRP for LPP treatment. The pilot study indicated that PRP significantly improved facial LPP lesions with no significant side effects. Further well-designed studies with a larger sample size, longer follow-up duration and possible longer treatment times are necessary to confirm this preliminary observation. Trial Registration: Thai Clinical Trials Registry identification number: TCTR20230202004 (https://www.thaiclinicaltrials.org/show/TCTR20230202004) approved on 02 February 2023.
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Registered trials
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