Evidence map›Paper›PMID 40213226›Full record

ArticleAnnals of medicine and surgery (2012)2025

Exploring the therapeutic potential of bimodal stimulation for tinnitus.

Ali Aamir Khan, Hamid Nasim, Gaffar Alemam A Manhal, Khabab Abbasher Hussien Mohamed Ahmed

Abstract readEditorial
In one paragraph

Article in Annals of medicine and surgery (2012), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ali Aamir KhanDepartment of Otorhinolaryngology, Ayub Medical College, Abbottabad, Khyber Pakhtunkhwa, Pakistan.
Hamid NasimDepartment of Otorhinolaryngology, Ayub Medical College, Abbottabad, Khyber Pakhtunkhwa, Pakistan.
Gaffar Alemam A ManhalFaculty of Medicine, University of Khartoum, Khartoum, Sudan.
Khabab Abbasher Hussien Mohamed AhmedFaculty of Medicine, University of Khartoum, Khartoum, Sudan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Tinnitus is the perception of sound without any external acoustic stimuli, affecting over 10% of the population, especially older adults. Current treatments focus on symptom management rather than a complete cure, often providing limited relief. Objective: To evaluate the efficacy and safety of bimodal neuromodulation therapy for tinnitus, compared to traditional treatment methods. Results: Bimodal neuromodulation, which combines sound and tongue stimulation, has shown significant improvement in tinnitus symptoms. FDA-approved studies report sustained symptom reduction in over 77% of patients for up to 12 months. The most common side effect is an increase in tinnitus symptoms, similar to sound-only treatments. Conclusion: This therapy presents a high benefit-to-risk ratio with minimal side effects, offering better clinical outcomes and patient satisfaction compared to existing treatments. Adjustments in treatment parameters can further enhance its effectiveness over time. Bimodal neuromodulation shows promise as a more effective treatment for tinnitus. Future clinical trials should replicate these positive findings, evaluate long-term effects, and compare their effectiveness to other treatment options to improve accessibility and clinical outcomes for tinnitus patients.

Indexed as

bimodal neuromodulation therapybimodal stimulationENTtherapeutic potentialtinnitus

Identifiers

PMID40213226
PMCPMC11981302

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.