Evidence map›Paper›PMID 40213224›Full record

ArticleAnnals of medicine and surgery (2012)2025

Progressive ataxia, cognitive decline, urinary incontinence, and unexplained hydrocephalus: a rare case of idiopathic normal pressure hydrocephalus in epileptic patient.

Raju Shah, Tek Nath Yogi, B C Pooja, Amrit Bhusal, Ashesh Koirala, Shailendra Katwal, Shishir Shahi, Rijan Kafle, Ranjan Shah

Abstract readCase Reports
In one paragraph

Article in Annals of medicine and surgery (2012), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Raju ShahBP Koirala Institute of Health Sciences (BPKIHS), Dharan, Koshi, Nepal.
Tek Nath YogiBP Koirala Institute of Health Sciences (BPKIHS), Dharan, Koshi, Nepal.
B C PoojaDepartment of Psychiatry; BP Koirala Institute of Health Sciences (BPKIHS), Dharan, Koshi, Nepal.
Amrit BhusalBP Koirala Institute of Health Sciences (BPKIHS), Dharan, Koshi, Nepal.
Ashesh KoiralaBP Koirala Institute of Health Sciences (BPKIHS), Dharan, Koshi, Nepal.
Shailendra KatwalDepartment of Radiology; Tribhuvan University Institute of Medicine, Kathmandu, Nepal.
Shishir ShahiBP Koirala Institute of Health Sciences (BPKIHS), Dharan, Koshi, Nepal.
Rijan KafleBP Koirala Institute of Health Sciences (BPKIHS), Dharan, Koshi, Nepal.
Ranjan ShahManipal Pokhara College of Medical Science, Pokhara, Kaski, Nepal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Idiopathic normal pressure hydrocephalus (iNPH) poses diagnostic challenges due to its overlapping symptoms with other neurodegenerative disorders. The clinical trial of gait disturbance, cognitive impairment, and urinary incontinence often mimics other conditions, making accurate diagnosis crucial. Case presentation: A 67-year-old male with a 40-year history of epilepsy presented with progressive gait abnormalities, cognitive decline, and bladder incontinence over 5 years. Initial evaluation revealed a magnetic gait, impaired short-term memory, and a Mini-Mental State Examination score of 17/30. MRI and CT scans showed ventriculomegaly without elevated cerebrospinal fluid (CSF) pressure. A lumbar puncture with a positive CSF tap test confirmed iNPH, and ventriculoperitoneal shunt surgery was performed, resulting in significant improvement in symptoms. Discussion: iNPH is characterized by the triad of gait disturbance, cognitive impairment, and urinary incontinence. Its diagnosis is primarily based on clinical presentation and neuroimaging. The CSF tap test is a crucial diagnostic tool, and shunt surgery remains the standard treatment. This case underscores the need for a high index of suspicion for iNPH in patients with atypical presentations and emphasizes the importance of long-term follow-up to monitor treatment efficacy. Conclusion: This case highlights the complexity of diagnosing iNPH, particularly in patients with comorbid conditions such as epilepsy. Thorough diagnostic evaluations and timely intervention are critical for improving patient outcomes. Long-term monitoring is essential to assess the effectiveness of treatment and manage potential complications.

Indexed as

cognitive impairmentgait disturbanceidiopathic normal pressure hydrocephaluslumbar punctureneuroimagingventriculoperitoneal shunt

Identifiers

PMID40213224
PMCPMC11981244

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