Evidence map›Paper›PMID 40213172›Full record

ArticleAnnals of medicine and surgery (2012)2025

Anti-inflammatory potential of royal jelly in multiple sclerosis disease: a double randomized clinical trial.

Susan Sabbagh, Zahra Eslamifar, Saba Behzadifard, Mohammad Reza Tabandeh, Mohammad Reza Zandi, Mahin Behzadifard

Abstract read
In one paragraph

Article in Annals of medicine and surgery (2012), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Royal jelly fermented byBiochemistry and biophysics reports · 2025
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Susan SabbaghDepartment of Anatomical Sciences, Faculty of Medicine, Dezful University of Medical Sciences, Dezful, Iran.
Zahra EslamifarDepartment of Medical Laboratory Sciences, School of Paramedical Sciences, Dezful University of Medical Sciences, Dezful, Iran.
Saba BehzadifardDepartment of Anatomical Sciences, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad Reza TabandehDepartment of Basic Sciences, Division of Biochemistry and Molecular Biology, Faculty of Veterinary Medicine, Shahid Chamran University, Ahvaz University of Medical Sciences, Ahvaz, Iran.
Mohammad Reza ZandiDepartment of Neurology, Ganjavian Hospital. Dezful University of Medical Sciences, Dezful, Iran.
Mahin BehzadifardDepartment of Medical Laboratory Sciences, School of Paramedical Sciences, Dezful University of Medical Sciences, Dezful, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Multiple sclerosis (MS) is a chronic, autoimmune, and neurodegenerative disease that affects the central nervous system. Royal jelly (RJ), a nutrient-rich substance known for its anti-inflammatory and antioxidant properties, holds potential in impeding disease progression by mitigating inflammatory processes and oxidative stress. This study was undertaken to explore the impact of RJ on oxidative stress and inflammatory markers in individuals diagnosed with MS. Methods: This randomized clinical trial involved the allocation of 35 MS patients into two groups: intervention ( Results: After the intervention, the mean EDSS score significantly decreased in the case group compared to pre-intervention ( Conclusion: Our findings suggest that RJ supplementation may have beneficial effects on inflammatory markers, oxidative stress indices and quality of life in MS patients.

Indexed as

inflammationmultiple sclerosisoxidative stressroyal jelly

Identifiers

PMID40213172
PMCPMC11981396

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.