ReviewAnnals of medicine and surgery (2012)2025
Spectrum of parathyroid disorders in Pakistan: a review article.
Review in Annals of medicine and surgery (2012), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Parathyroid abnormalities and gland diseases are classified as hyperparathyroidism and hypoparathyroidism. These conditions are often discovered incidentally during screenings for abnormal serum calcium levels, typically conducted for renal or bone diseases and other disorders. Parathyroid hormone (PTH) plays a crucial biological role in maintaining ionized calcium and phosphate levels within the normal range by activating specific receptor-mediated cell responses throughout the body. Compared to the Western world, Pakistan has significantly fewer publications on parathyroid diseases. Most available research comprises case reports, small case series, or retrospective studies, often including approximately 100 studies. In this article, we describe the demographics and varied clinical presentations of parathyroid gland disorders in the Pakistani population. Additionally, we provide a summary of biochemical parameters and localization strategies used in these cases. A compiled record of parathyroid gland disorders in Pakistan is currently lacking, and this article aims to bridge that gap by presenting a comprehensive review of all reported cases. This review includes a summary of 54 studies, comprising retrospective studies and case reports, highlighting the clinical variability of parathyroid (PTH) disorders in Pakistan. According to the literature, 0.5% of patients were asymptomatic, while the mean duration of symptoms among symptomatic patients was 3.03 years. Unlike Western populations, laboratory findings from Pakistani patients show elevated levels of serum calcium, serum PTH, and serum alkaline phosphate. Common clinical features included abdominal pain, dysphagia, and vitamin D deficiency, along with constitutional symptoms such as arthralgias, myalgias, fatigue, and headache. Psychiatric complications, particularly clinical depression, and pathological fractures emerged as the most frequent complications associated with PTH disorders in Pakistan.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.