Azithromycin-induced Adolescent Manic Episode with Psychotic Features: A Case Report.

Amro H Mohammad, Marie-Pier Lecours, Emmanuel Adams-Gelinas, Arshia Kakkar, Anthi Stefatos

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In one paragraph

Article in Innovations in clinical neuroscience. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Amro H MohammadDr. Mohammad, Mr. Adams-Gelinas, and Dr. Kakkar are with the Faculty of Medicine and Health Sciences at McGill University in Montreal, Quebec, Canada.

Marie-Pier LecoursDr. Lecours is with Hôpital Pierre-Boucher in Longueuil, Quebec, Canada.

Emmanuel Adams-GelinasDr. Mohammad, Mr. Adams-Gelinas, and Dr. Kakkar are with the Faculty of Medicine and Health Sciences at McGill University in Montreal, Quebec, Canada.

Arshia KakkarDr. Mohammad, Mr. Adams-Gelinas, and Dr. Kakkar are with the Faculty of Medicine and Health Sciences at McGill University in Montreal, Quebec, Canada.

Anthi StefatosDr. Stefatos is with the Department of Psychiatry at McGill University in Montreal, Quebec, and the Department of Psychiatry, Integrated University Health and Social Services Center of the West Island of Montreal (CIUSSS ODIM) in Pointe-Claire, Quebec, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Premarketing clinical trials of azithromycin (AZT) computed a 0.8-percent incidence rate of neurological symptoms, such as headaches and vertigo. Postmarket surveillance reported on psychiatric reactions to AZT that included aggression, agitation, anxiety, delirium, and hallucinations. Nonetheless, these observations do not provide further insight on patient characteristics, disease course, and medical intervention. Methods: We report the case of an 18-year-old male patient with no prior medical or psychiatric history who developed profound religious delusions and unusual behavior hours after taking a one-time AZT dose of 1,000mg for a confirmed sexually transmitted Results: The patient presentation and clinical history satisfied criteria for a manic episode with psychotic features lasting for at least one week. As per Conclusion: We report, to our knowledge for the first time, that AZT monotherapy might induce a manic episode with psychotic features in adolescent patients with no psychiatric medical history.

Indexed as

Azithromycinmacrolidemanic episode

Identifiers

PMID40213123

PMCPMC11980907

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.