Evidence map›Paper›PMID 40213056›Full record

ArticleSmall science2021

3D Electrospun Synthetic Extracellular Matrix for Tissue Regeneration.

Yingchun Su, Mette Steen Toftdal, Alice Le Friec, Mingdong Dong, Xiaojun Han, Menglin Chen

Abstract read
In one paragraph

Article in Small science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Small Diameter Vascular Grafts Made in Minutes.Advanced materials (Deerfield Beach, Fla.) · 2026
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. 3D Electrospinning of Macroscopic PLLA Structures.Macromolecular rapid communications · 2025
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yingchun SuState Key Laboratory of Urban Water Resource and Environment School of Chemistry and Chemical Engineering Harbin Institute of Technology Harbin 150001 China.
Mette Steen ToftdalDepartment of Biological and Chemical Engineering Aarhus University DK-8000 Aarhus C Denmark.
Alice Le FriecDepartment of Biological and Chemical Engineering Aarhus University DK-8000 Aarhus C Denmark.
Mingdong DongInterdisciplinary Nanoscience Center (iNANO) Aarhus University DK-8000 Aarhus C Denmark.ORCID 0000-0002-2025-2171
Xiaojun HanState Key Laboratory of Urban Water Resource and Environment School of Chemistry and Chemical Engineering Harbin Institute of Technology Harbin 150001 China.ORCID 0000-0001-8571-6187
Menglin ChenDepartment of Biological and Chemical Engineering Aarhus University DK-8000 Aarhus C Denmark.ORCID 0000-0002-2721-651X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electrospinning is considered the most versatile micro-/nanofiber fabrication technology. The electrospun fibers hold high surface area, desired mechanical properties, controlled topography, as well as the ease of biochemical functionalization. The 3D electrospun fibrous structures closely mimic the hierarchical architecture and fibrous features of the extracellular matrices (ECM), which greatly contribute to biomaterials design to stimulate tissue regeneration. Herein, the recent advances in electrospinning technology for 3D production of ECM-mimicking biomaterial scaffolds are systematically summarized and the applications in neural, cardiac, bone, skin, and vascularized tissue regeneration are thoroughly discussed. Challenges and future scopes related to each field of tissue regeneration are discussed after each subsection. A few examples of liver, kidney, esophageal tissue engineering are also discussed. Finally, the key challenge in the cost-effective upscale of the electrospinning technique to mature and prevalent industrial applications is outlined. Herein, a systematic, thorough summary of the recent evolutions in electrospinning and its emerging applications for a broad range of tissue regenerations is provided.

Indexed as

3D electrospun structuresnative extracellular matricestissue engineeringtissue regeneration

Identifiers

PMID40213056
PMCPMC11935887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.