Article in Small science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
14 authors.
Jingjing GuKey Laboratory of Spine and Spinal Cord Injury Repair and Regeneration Ministry of Education Tongji Hospital The Institute for Biomedical Engineering & Nano Science School of Medicine Tongji University Shanghai 200092 P. R. China.
Jiao ChangShanghai Skin Disease Hospital The Institute for Biomedical Engineering & Nano Science School of Medicine Tongji University Shanghai 200092 P. R. China.
Shiyu ChenKey Laboratory of Spine and Spinal Cord Injury Repair and Regeneration Ministry of Education Tongji Hospital The Institute for Biomedical Engineering & Nano Science School of Medicine Tongji University Shanghai 200092 P. R. China.
Hui ZhiKey Laboratory of Spine and Spinal Cord Injury Repair and Regeneration Ministry of Education Tongji Hospital The Institute for Biomedical Engineering & Nano Science School of Medicine Tongji University Shanghai 200092 P. R. China.
Jiuyuan SunShanghai Skin Disease Hospital The Institute for Biomedical Engineering & Nano Science School of Medicine Tongji University Shanghai 200092 P. R. China.
Weimin YinKey Laboratory of Spine and Spinal Cord Injury Repair and Regeneration Ministry of Education Tongji Hospital The Institute for Biomedical Engineering & Nano Science School of Medicine Tongji University Shanghai 200092 P. R. China.
Tingting ZhangShanghai Skin Disease Hospital The Institute for Biomedical Engineering & Nano Science School of Medicine Tongji University Shanghai 200092 P. R. China.
Jie ZangShanghai Skin Disease Hospital The Institute for Biomedical Engineering & Nano Science School of Medicine Tongji University Shanghai 200092 P. R. China.
Yuge ZhaoShanghai Skin Disease Hospital The Institute for Biomedical Engineering & Nano Science School of Medicine Tongji University Shanghai 200092 P. R. China.
Yiqiong LiuShanghai Skin Disease Hospital The Institute for Biomedical Engineering & Nano Science School of Medicine Tongji University Shanghai 200092 P. R. China.
Xiao ZhengShanghai Skin Disease Hospital The Institute for Biomedical Engineering & Nano Science School of Medicine Tongji University Shanghai 200092 P. R. China.
Leiyu FengState Key Laboratory of Pollution Control and Resources Reuse School of Environmental Science and Engineering Tongji University Shanghai 200092 P. R. China.
Yongyong LiShanghai Skin Disease Hospital The Institute for Biomedical Engineering & Nano Science School of Medicine Tongji University Shanghai 200092 P. R. China.
Haiqing DongKey Laboratory of Spine and Spinal Cord Injury Repair and Regeneration Ministry of Education Tongji Hospital The Institute for Biomedical Engineering & Nano Science School of Medicine Tongji University Shanghai 200092 P. R. China.ORCID https://orcid.org/0000-0001-6428-5904
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itself
Abstract
Cell metabolite adenosine can induce extensive and persistent immunosuppression by binding to adenosine receptors on immune cells. Seriously, the hypoxia-driven adenosinergic axis aggravates adenosine accumulation via dephosphorizing immune-activating adenosine triphosphate (ATP) released during immunogenic cell death (ICD). Different from direct adenosine clearance or adenosine receptor blockade or directly using ecto-enzyme (CD39/CD73) antagonist, it is hoped to use an innovative small science engineering to regulate the upstream hypoxia/HIF-1α signal of the hypoxia-adenosinergic axis, thereby reducing the immunosuppressive extracellular adenosine and enhancing ICD-triggered antitumor immunity. PM@Mn is constructed by gradually integrating metformin and MnO
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Suppressing the Hypoxia-Adenosinergic Axis by a Tailored Nanoreactor for Enhanced Photothermal Immunotherapy. · full record | OpenQuestion