Evidence map›Paper›PMID 40212947›Full record

ArticleFrontiers in veterinary science2025

Case Report: Presumed cerebral salt wasting syndrome in a 10-week-old German Shorthaired Pointer.

Elizabeth Jackson, Gilad Fefer, Karen R Muñana, Bernie D Hansen

Abstract readCase Reports
In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Elizabeth JacksonDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, United States.
Gilad FeferDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, United States.
Karen R MuñanaDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, United States.
Bernie D HansenDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case report describes a rare presentation of cerebral salt-wasting syndrome (CSW) in a 10-week-old German Shorthaired Pointer following a traumatic brain injury. The patient presented stuporous and tetraplegic with advanced imaging revealing a depressed skull fracture and active brain hemorrhage. Following surgical intervention, the dog exhibited persistent hypovolemia and hyponatremia prompting treatment with intravenous hypertonic saline and enteral sodium supplementation. Positive response to sodium supplementation, coupled with elevated fractional excretion of uric acid (FEUA) despite clinical improvement, supported the diagnosis of CSW. This report contributes novel insights into CSW in veterinary medicine, emphasizing the distinctive features of its presentation, diagnostic considerations, and treatment responses. The clinical utility of FEUA as a diagnostic tool is highlighted for the first time in a canine patient, providing a valuable tool for differentiation. This information enhances veterinary practitioners' awareness, facilitating more accurate diagnoses and tailored treatment strategies for similar cases in the future.

Indexed as

caninehyponatremiahypovolemiaskull fracturetraumatic brain injury

Identifiers

PMID40212947
PMCPMC11983543

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.