Evidence map›Paper›PMID 40212946›Full record

ArticleOTA international : the open access journal of orthopaedic trauma2025

Revisiting the OTA-OFC: a systematic review of open fracture classification studies since 2010.

Babapelumi Adejuyigbe, Mohini Gharpure, Ria Tilve, Shravya Kakulamarri, Sophia Wang, Jennifer Kallini, Ashley E Levack, Rachel Seymour, Meir Marmor

Abstract read
In one paragraph

Article in OTA international : the open access journal of orthopaedic trauma, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Babapelumi AdejuyigbeInstitute of Global Orthopedics and Traumatology (IGOT), San Francisco, CA.ORCID https://orcid.org/0000-0001-7373-3596
Mohini GharpureMedical College of Georgia, Augusta, GA.
Ria TilveInstitute of Global Orthopedics and Traumatology (IGOT), San Francisco, CA.
Shravya KakulamarriInstitute of Global Orthopedics and Traumatology (IGOT), San Francisco, CA.
Sophia WangInstitute of Global Orthopedics and Traumatology (IGOT), San Francisco, CA.
Jennifer KalliniDepartment of Orthopaedic Surgery, University of California, Los Angeles, Los Angeles, CA.
Ashley E LevackDepartment of Orthopaedic Surgery & Rehabilitation, Loyola University Medical Center, Maywood, IL.
Rachel SeymourAtrium Health, Charlotte, NC.
Meir MarmorZuckerberg San Francisco General Hospital, Orthopaedic Trauma Institute, University of California San Francisco, San Francisco, CA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Management of open extremity fractures presents significant challenges due to infection risks and healing complications. The widely used Gustilo-Anderson classification, established in 1976, categorizes open fractures primarily by wound size. However, it has been criticized for its poor reliability and lack of crucial outcome measures. In 2010, the Orthopaedic Trauma Association open fracture classification (OTA-OFC) was introduced as a more detailed alternative. Despite its reported advantages in reproducibility and predictive ability, the OTA-OFC has not seen widespread clinical adoption. Understanding how the OTA-OFC has been used since its inception may clarify its impact on medical care and the reasons for its slow acceptance. Objectives: To assess the usage, benefits, and limitations of the OTA-OFC by a systematic review of all publications that used the OTA-OFC since its inception in 2010. Methods: Data Sources: A comprehensive search of Google Scholar, Medline/PubMed, Embase, and Cochrane Database was conducted with the following search terms: [Orthopedic Trauma Association] OR [OTA] AND [Open Fracture Classification] OR [OFC]. Study Selection: Articles written in English, published between 2010 and 2024, and using the OTA-OFC for research/clinical assessment purposes were included. Data Extraction: Data were extracted using Covidence. Extracted data included context of OTA-OFC use, benefits and limitations associated with OTA-OFC, and other descriptive information including study design and number of patients. Data Synthesis: Data were compiled, analyzed, and synthesized using Microsoft Excel. Results/Conclusions: Although OTA-OFC provides more detailed fracture classification with better outcome predictions, its complexity limits its routine use. Increased clinical evidence and streamlined communication are needed to promote broader acceptance.

Indexed as

Gustilo-Anderson classification (GAC)open fracture classificationOrthopaedic Trauma Association open fracture classification (OTA-OFC)predictive abilitywound classification

Identifiers

PMID40212946
PMCPMC11984759

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.