Evidence map›Paper›PMID 40212930›Full record

ArticleOphthalmology science

The Role of Menopause and Its Association with the Apolipoprotein E4 Allele for Age at Diagnosis of Glaucoma in Women.

Yan Shi, William Liu, Junming Hu, Wei Qiao Qiu, Xinyue He, Yan Gao, Xiaoling Zhang, Zhigang Fan

Abstract read
In one paragraph

Article in Ophthalmology science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yan ShiBeijing Tongren Eye Center Research Ward, Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing Tongren Hospital, Beijing Institute of Ophthalmology, Capital Medical University, Beijing, China.
William LiuYale University, New Haven, Connecticut.
Junming HuDepartments of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, Massachusetts.
Wei Qiao QiuDepartments of Psychiatry and Pharmacology, Alzheimer's Disease Center, Boston University School of Medicine, Boston, Massachusetts.
Xinyue HeBeijing Tongren Eye Center Research Ward, Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing Tongren Hospital, Beijing Institute of Ophthalmology, Capital Medical University, Beijing, China.
Yan GaoBeijing Tongren Eye Center Research Ward, Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing Tongren Hospital, Beijing Institute of Ophthalmology, Capital Medical University, Beijing, China.
Xiaoling ZhangDepartments of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, Massachusetts.
Zhigang FanBeijing Tongren Eye Center Research Ward, Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing Tongren Hospital, Beijing Institute of Ophthalmology, Capital Medical University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To explore the impact of menopause for age at diagnosis (AAD) of glaucoma in women and illustrate its interaction with the apolipoprotein E ( Design: A retrospective, case-only analysis using the UK Biobank participants with complete data (2006-2010) for analysis. Participants: One thousand three hundred fifty-eight female glaucoma patients. Methods: Multivariable-adjusted associations of AAD of glaucoma, Main Outcome Measures: Age at diagnosis of glaucoma, age of menopause, Results: The age-adjusted univariate LMM showed that later menopause was significantly associated with an older AAD of glaucoma in both the overall cohort and subgroups where glaucoma developed before or after menopause (model 1, all Conclusions: Later menopause was associated with an older AAD of glaucoma, with the Financial Disclosures: The author(s) have no proprietary or commercial interest in any materials discussed in this article.

Indexed as

Age at diagnosis of glaucomaAlzheimer's diseaseAPOE E4 alleleMenopauseUK Biobank

Identifiers

PMID40212930
PMCPMC11985040

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.