Evidence map›Paper›PMID 40212888›Full record

ArticleFrontiers in computational neuroscience2025

Prefrontal meta-control incorporating mental simulation enhances the adaptivity of reinforcement learning agents in dynamic environments.

JiHun Kim, Jee Hang Lee

Abstract read
In one paragraph

Article in Frontiers in computational neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

JiHun KimGraduate School of AI and Informatics, Sangmyung University, Seoul, Republic of Korea.
Jee Hang LeeGraduate School of AI and Informatics, Sangmyung University, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Recent advances in computational neuroscience highlight the significance of prefrontal cortical meta-control mechanisms in facilitating flexible and adaptive human behavior. In addition, hippocampal function, particularly mental simulation capacity, proves essential in this adaptive process. Rooted from these neuroscientific insights, we present Methods: This architectural framework implements prefrontal meta-control mechanisms integrated with hippocampal replay function, which in turn optimized task performance with limited experiences. We evaluated this approach through comprehensive experimental simulations across three distinct paradigms: the two-stage Markov decision task, which frequently serves in human learning and decision-making research; Results: Experimental results demonstrate Discussions: These findings advance our understanding of computational reinforcement learning whilst contributing to the development of brain-inspired learning agents capable of flexible, goal-directed behavior within dynamic environments.

Indexed as

mental simulationmodel-based learning strategymodel-free learning strategyneuroscience of reinforcement learningprefrontal meta-controlreinforcement learning agents

Identifiers

PMID40212888
PMCPMC11983510

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.