Evidence map›Paper›PMID 40212787›Full record

ReviewF1000Research2024

Fostering healthcare system sustainability through efficient practices: Can adopting biosimilars ease the financial burden of rheumatoid arthritis?

Christos Ntais, Nikolaos Kontodimopoulos, John Fanourgiakis, Michael A Talias

Abstract readReview
In one paragraph

Review in F1000Research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Christos NtaisHealthcare Management Program, School of Economics & Management, Open University of Cyprus, Nicosia, Cyprus.ORCID https://orcid.org/0000-0002-2749-101X
Nikolaos KontodimopoulosHealthcare Management Program, School of Social Sciences, Hellenic Open University, Patras, Greece.
John FanourgiakisHealthcare Management Program, School of Social Sciences, Hellenic Open University, Patras, Greece.ORCID https://orcid.org/0000-0001-5364-7412
Michael A TaliasHealthcare Management Program, School of Economics & Management, Open University of Cyprus, Nicosia, Cyprus.ORCID https://orcid.org/0000-0002-1802-5586

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune-mediated inflammatory diseases like rheumatoid arthritis (RA) have been successfully treated using biologic disease-modifying antirheumatic drugs. These medications are not utilized as first-line treatment, in part because of their high cost, but they are frequently seen to be cost-effective for RA patient populations that do not respond adequately to conventional disease-modifying antirheumatic drugs. Moreover, not all RA patients who meet clinical eligibility criteria can access biologics, not even as second-line therapy. Recently, there has been an increasing interest in biosimilars that are highly comparable to their originator biologics in terms of efficacy and safety but generally come at a lower price. This review summarizes the potential role of biosimilars in reducing RA expenditure and increasing RA patient access to biologic therapies. As the global landscape for biosimilars continues to evolve, it is essential to consider the unique challenges and opportunities in different healthcare systems. By leveraging the potential of biosimilars, healthcare systems can improve RA management, ease its economic burden and ensure that patients have access to effective and affordable treatments. The future of RA treatment lies in the integration of biosimilars into clinical practice, offering hope for more sustainable and equitable healthcare systems.

Indexed as

Antirheumatic AgentsArthritis, RheumatoidBiosimilar PharmaceuticalsDelivery of Health CareCost-Benefit AnalysisHumansAntirheumatic AgentsBiosimilar Pharmaceuticalsbiologicsbiosimilarsbudget impact analysiscost-effectiveness analysispharmacoeconomicsrheumatoid arthritis

Identifiers

PMID40212787
PMCPMC11983381

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.