Evidence map›Paper›PMID 40212781›Full record

ArticleBioactive materials2025

Continuous mechanical-gradient hydrogel with on-demand distributed Mn

Junwei Xu, Yi Cui, Ping Li, Xuemei Sun, Zhiheng Chen, Jingxi Wang, Xuenan Gu, Xiaogang Wang, Yubo Fan

Abstract read
In one paragraph

Article in Bioactive materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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  16. Future Frontiers in Bioinspired Implanted Biomaterials.Advanced materials (Deerfield Beach, Fla.) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Junwei XuSchool of Biological Science and Medical Engineering, Beihang University, Beijing, 100191, China.
Yi CuiSchool of Biological Science and Medical Engineering, Beihang University, Beijing, 100191, China.
Ping LiSchool of Biological Science and Medical Engineering, Beihang University, Beijing, 100191, China.
Xuemei SunSchool of Biological Science and Medical Engineering, Beihang University, Beijing, 100191, China.
Zhiheng ChenSchool of Biological Science and Medical Engineering, Beihang University, Beijing, 100191, China.
Jingxi WangSchool of Biological Science and Medical Engineering, Beihang University, Beijing, 100191, China.
Xuenan GuSchool of Biological Science and Medical Engineering, Beihang University, Beijing, 100191, China.
Xiaogang WangThe Third Affiliated Hospital of Southern Medical University, Southern Medical University, Guangzhou, 528300, China.
Yubo FanSchool of Biological Science and Medical Engineering, Beihang University, Beijing, 100191, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traditional layered gradient scaffolds are susceptible to delamination owing to abrupt stress alterations, thereby rendering them inefficacious for the integrated repair of osteochondral defects. This study proposed a novel hydrogel possessing continuous magnetic-mechanical and multiple functional metal elements gradients. The establishment of these gradients within the hydrogel was accomplished by first applying a magnetic field to FMHM particles (Fe

Indexed as

Continuous mechanical gradientManganeseMg-doped hydroxyapatiteOsteochondral regenerationYAP1

Identifiers

PMID40212781
PMCPMC11985089

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.