ArticleBioactive materials2025
Continuous mechanical-gradient hydrogel with on-demand distributed Mn
Article in Bioactive materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed.
- Mechano-immunomodulatory biomaterials: From immune mechanosensing to translational design.Bioactive materials · 2026Review
- Dynamic Biomaterial: A Platform for Biomedical Applications With Multiple Preparation Strategies.Macromolecular rapid communications · 2026Review
- Mechanobiology of orofacial tissues: principles, mechanisms, and therapeutic applications.International journal of oral science · 2026Review
- Innovative Hydroxyapatite-Hydrogel Composites for Cartilage Regeneration.Gels (Basel, Switzerland) · 2026Review
- Programmable continuous gradient bioprinting for engineering spatially heterogeneous microenvironments.Materials today. Bio · 2026Article
- Recent Advancements in Sodium Alginate-Based Hydrogels Combined with Magnetic Nanoparticles for Biological Applications: A Review.Gels (Basel, Switzerland) · 2026Review
- High-performance hydrogels in orthopedics: Structural design, performance tuning, and clinical potential.Materials today. Bio · 2026Review
- A decoupling strategy toward spatiotemporal regulation and biomechanical transmission of sandwiched scaffold for osteochondral regeneration.Nature communications · 2026Article
- Biomimetic Gradient Lubrication Hydrogel Contrived by Self-Reinforced MOFs Nanoparticle Network.Nano-micro letters · 2026Article
- Integrated 3D printing of topologically hierarchical mechanical hydrogel for accelerating osteochondral regeneration.Bioactive materials · 2026Article
- Advances in Injectable miRNA-Loaded Nanocomposite Hydrogel Systems for Cartilage Repair in KOA.International journal of nanomedicine · 2026Review
- Research Progress of Ferrosoferric Oxide Nanoparticles in Bone Regeneration and Disease Treatment.International journal of nanomedicine · 2026Review
- Biomimetic gradient hydrogels for osteochondral regeneration: from multi-dimensional design to clinical translation.Frontiers in bioengineering and biotechnology · 2026Review
- Hydrogels for Osteochondral Interface Regeneration: Biomaterial Types, Processes, and Animal Models.Gels (Basel, Switzerland) · 2025Review
- Research Progress of Sodium Alginate-Based Hydrogels in Biomedical Engineering.Gels (Basel, Switzerland) · 2025Review
- Future Frontiers in Bioinspired Implanted Biomaterials.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Nanomaterial-based encapsulation of biochemicals for targeted sepsis therapy.Materials today. Bio · 2025Review
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Traditional layered gradient scaffolds are susceptible to delamination owing to abrupt stress alterations, thereby rendering them inefficacious for the integrated repair of osteochondral defects. This study proposed a novel hydrogel possessing continuous magnetic-mechanical and multiple functional metal elements gradients. The establishment of these gradients within the hydrogel was accomplished by first applying a magnetic field to FMHM particles (Fe
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.