ArticleBioactive materials2025
Artificial multienzyme nanoflower composite hydrogel for efficiently promoting MRSA-infected diabetic wound healing via glucose-activated NO releasing and microenvironment regulation.
Article in Bioactive materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Harnessing gasotransmitters for orthopaedic infection therapy: Mechanisms and advanced delivery platforms.Bioactive materials · 2027Review
- Multifunctional Hydrogel Dressing Loaded with DH-EVs Promotes Healing of Bacteria-Infected Diabetic Wounds.Nanomaterials (Basel, Switzerland) · 2026Article
- Spatiotemporally responsive hybrid hydrogels for sequential therapy and visualized monitoring of multidrug-resistant bacterial wound infections.Bioactive materials · 2026Article
- Research Progress on Antibacterial Strategies of pH-Responsive Hydrogel Dressings in Chronic Wound Management.Macromolecular bioscience · 2026Review
- Hydrogels: current biomedical applications and future directions.Molecular biomedicine · 2026Review
- Defect-Engineered Porous CAdvanced healthcare materials · 2026Article
- Multifunctional Hydrogels for Diabetic Wound Healing: Design Strategies and Microenvironmental Remodeling Mechanisms.Gels (Basel, Switzerland) · 2026Review
- Near-infrared light-driven photocatalytic reactive oxygen species-generating antibacterial and self-shrinking hybrid hydrogels for combating drug-resistant bacterial biofilm infection and accelerating wound healing.Bioactive materials · 2026Article
- A Multifunctional ε-Polylysine/Hyaluronic Acid Hydrogel Promotes Diabetic Wound Healing by Orchestrating Multidimensional Synergy.Pharmaceutics · 2026Article
- Multifunctional Selenium-Sulfur-Doped Carbon Dots Nanozymes with Thioredoxin Reductase Activity for Regenerative Therapy of Infected Wounds.ACS applied materials & interfaces · 2026Article
- An antioxidant and injectable hydrogel dressing for repairing MRSA biofilm-infected diabetic wounds.Journal of nanobiotechnology · 2026Article
- Functionalized hydrogel sequentially deliver tannic acid and bioactive probiotics for radiation-induced skin injury.Materials today. Bio · 2026Article
- Injectable platelet-rich plasma-based hydrogels: a controlled release platform for growth factors and cardiac regeneration post-myocardial infarction.Regenerative biomaterials · 2026Article
- Stimuli-responsive hydrogels based on cascade reactions: a novel strategy to promote the efficient repair of diabetic wounds.Theranostics · 2026Review
- Harnessing stromal vascular fraction-based therapies for wound healing: Mechanisms, synergies, and clinical translation.Regenerative therapy · 2025Review
- Trimetallic Nanozyme-Embedded Smart Hydrogel Enables NIR-Controlled Bacterial Killing and Oxidative Stress Alleviation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Hybrid metallic nanozyme with nitric oxide-releasing photothermal coating for accelerated infected diabetic wound healing.Journal of nanobiotechnology · 2025Article
- Nanomaterial-based encapsulation of biochemicals for targeted sepsis therapy.Materials today. Bio · 2025Review
- PtPdNi Trimetallic-Doped MIL-88 Hydrogel Accelerates Healing of Bacterial-Infected Diabetic Wounds.International journal of nanomedicine · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diabetic wound repair is a global challenge due to bacterial infection and the typical microenvironments of hyperglycemia, high pH value, hypoxia, persistent inflammation and insufficient angiogenesis. Herein, a glucose-activated nitric oxide (NO) releasing and microenvironment regulation hydrogel dressing (COH-GB) has been developed for efficiently promoting infectious diabetic wound healing. Specifically, an artificial multienzyme nanoflower (GB nanoflower) composed of glucose oxidase (GOx) and hemoglobin (Hb) was synthesized and incorporated into the hydrogel formed by carboxymethyl chitosan (CMCS), oxidized sodium alginate (OSA) and hydroxyurea (HU). In which, the hyperglycemia-triggered cascade reaction could consume glucose, while providing hydrogen peroxide (H
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.