Evidence map›Paper›PMID 40212760›Full record

ArticleSmall science2024

Bioinspired Bone Seed 3D-Printed Scaffold via Trapping Black Phosphorus Nanosheet for Bone Regeneration.

Zhengwei Cai, Zhijie Chen, Yuan Tang, Liang Cheng, Minglong Qiu, Ningtao Wang, Wei Jiang, Zhanchun Li, Catarina Leite Pereira, Yunhai Zhang and 2 more

Abstract read
In one paragraph

Article in Small science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zhengwei CaiDepartment of Orthopaedics Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases Shanghai Institute of Traumatology and Orthopaedics Ruijin Hospital Shanghai Jiao Tong University School of Medicine 197 Ruijin 2nd Road Shanghai 200025 P. R. China.
Zhijie ChenDepartment of Orthopaedics Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases Shanghai Institute of Traumatology and Orthopaedics Ruijin Hospital Shanghai Jiao Tong University School of Medicine 197 Ruijin 2nd Road Shanghai 200025 P. R. China.
Yuan TangDepartment of Orthopaedics Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases Shanghai Institute of Traumatology and Orthopaedics Ruijin Hospital Shanghai Jiao Tong University School of Medicine 197 Ruijin 2nd Road Shanghai 200025 P. R. China.
Liang ChengDepartment of Orthopaedic Surgery Renji Hospital, School of Medicine Shanghai Jiao Tong University Shanghai 200127 P. R. China.
Minglong QiuDepartment of Orthopaedics Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases Shanghai Institute of Traumatology and Orthopaedics Ruijin Hospital Shanghai Jiao Tong University School of Medicine 197 Ruijin 2nd Road Shanghai 200025 P. R. China.
Ningtao WangDepartment of Orthopaedics Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases Shanghai Institute of Traumatology and Orthopaedics Ruijin Hospital Shanghai Jiao Tong University School of Medicine 197 Ruijin 2nd Road Shanghai 200025 P. R. China.
Wei JiangDepartment of Orthopedics The First Affiliated Hospital of Anhui Medical University 218 Jixi Road Shushan District Hefei Anhui 230022 P. R. China.
Zhanchun LiDepartment of Orthopaedic Surgery Renji Hospital, School of Medicine Shanghai Jiao Tong University Shanghai 200127 P. R. China.
Catarina Leite PereiraI3-Instituto de Investigação e Inovação Em Saúde and INEB-Instituto de Engenharia Biomédica Universidade Do Porto Rua Alfredo Allen 208 4200-135 Porto Portugal.
Yunhai ZhangDepartment of Orthopaedics Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases Shanghai Institute of Traumatology and Orthopaedics Ruijin Hospital Shanghai Jiao Tong University School of Medicine 197 Ruijin 2nd Road Shanghai 200025 P. R. China.
Bruno SarmentoI3-Instituto de Investigação e Inovação Em Saúde and INEB-Instituto de Engenharia Biomédica Universidade Do Porto Rua Alfredo Allen 208 4200-135 Porto Portugal.ORCID https://orcid.org/0000-0001-5763-7553
Wenguo CuiDepartment of Orthopaedics Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases Shanghai Institute of Traumatology and Orthopaedics Ruijin Hospital Shanghai Jiao Tong University School of Medicine 197 Ruijin 2nd Road Shanghai 200025 P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significance of endogenous mineralization in bone reconstruction is paramount, as it facilitates the accumulation of calcium ions for bone tissue deposition. However, conventional 3D-printed scaffolds lack the capacity for calcium ion enrichment and mineralization, coupled with their low bone inductive activity. Inspired from the development of natural plant seeds, a biomimetic 3D printing scaffold is developed by implanting photosensitive black phosphorus "bone seeds" (BS), guiding a sequential process mirroring rooting (osteoblast recruitment), sprouting (fibrous callus mineralization), flowering (osseous callus formation), and fruiting (callus plasticity). BS were trapped onto porous 3D polycaprolactone (PCL) scaffolds with aminated surfaces

Indexed as

black phosphorusbone regenerationsbone seedsendogenous mineralizations, 3D scaffolds

Identifiers

PMID40212760
PMCPMC11935154

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.