Evidence map›Paper›PMID 40212729›Full record

ArticleThe Science of the total environment2025

Wastewater Based Measures of COVID-19 and Associations with Children's Absenteeism at Grade Schools.

Helena M Solo-Gabriele, Gabriela Guevara, Naresh Kumar, Ayaaz Amirali, Kristina M Babler, Cynthia C Beaver, Samuel Comerford, Maria Ferraris, Natasha Schaefer Solle, Mark E Sharkey and 1 more

Abstract read
In one paragraph

Article in The Science of the total environment, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Culture, qPCR, and genome-based surveillance ofFrontiers in microbiology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Helena M Solo-GabrieleDepartment of Chemical, Environmental, and Materials Engineering, University of Miami, Coral Gables, FL USA.
Gabriela GuevaraDepartment of Pediatrics, University of Miami Miller School of Medicine, Miami, FL USA.
Naresh KumarDepartment of Public Health Sciences, University of Miami Miller School of Medicine, Miami, FL USA.
Ayaaz AmiraliDepartment of Chemical, Environmental, and Materials Engineering, University of Miami, Coral Gables, FL USA.
Kristina M BablerDepartment of Chemical, Environmental, and Materials Engineering, University of Miami, Coral Gables, FL USA.
Cynthia C BeaverDepartment of Medicine, University of Miami Miller School of Medicine, Miami, FL USA.
Samuel ComerfordDepartment of Medicine, University of Miami Miller School of Medicine, Miami, FL USA.
Maria FerrarisDepartment of Pediatrics, University of Miami Miller School of Medicine, Miami, FL USA.
Natasha Schaefer SolleDepartment of Medicine, University of Miami Miller School of Medicine, Miami, FL USA.
Mark E SharkeyDepartment of Medicine, University of Miami Miller School of Medicine, Miami, FL USA.
Lisa GwynnDepartment of Pediatrics, University of Miami Miller School of Medicine, Miami, FL USA.

Funding

Supplement for MINI point-of-use deviceU01DA053941 · NIDA · UNIVERSITY OF MIAMI CORAL GABLES · PI MASON, CHRISTOPHER EDWARD, SCHURER, STEPHAN C · 2021 to 2022
$5.2M
Assessing Testing Strategies for Safe Return to K-12 Schools in an Underserved PopulationOT2HD107557 · NICHD · WASHINGTON UNIVERSITY · PI NEWLAND, JASON · 2021 to 2022
$4.0M
Maximizing Child Health and Learning Potential:How to Promote A School Culture of Safety in the era of COVID-19OT2HD108111 · NICHD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI GWYNN, LISA A., PULGARON, ELIZABETH ROSE · 2021 to 2022
$3.6M
NICHD NIH HHS OT2 HD107557NICHD NIH HHS OT2 HD108111NIDA NIH HHS U01 DA053941
6 · The paper itself

Abstract

During the COVID-19 pandemic schools closed due to concerns over disease spread resulting in lost learning opportunities. One approach for documenting disease spread includes wastewater (WW) surveillance of the virus that causes COVID-19 (Severe Acute Respiratory Syndrome Coronavirus 2, SARS-CoV-2) and other infectious pathogens. The objective of this study was to evaluate whether wastewater can be used to track children's health at grade schools in an underserved community, which was vulnerable due to limited health-based data and difficulties in implementing mitigation measures. The 18-month study was initiated during January 2022 at 9 grade schools (3 high, 2 middle, and 4 elementary schools) characterized as low income. Children's health was evaluated through absenteeism due to difficulties in attaining representative clinical diagnoses through school-based clinics. Wastewater measurements of SARS-CoV-2 were available weekly through grab sample collection and RNA extraction followed by quantification using qPCR. The average absenteeism rate was 7.1%, ranging from 4.6% to 12.5% per school. Fraction of WW samples positive for SARS-CoV-2 was 38% with SARS-Cov-2 levels ranging from detection limits (100 gc/L) to a maximum of 10.2 million gc/L. When data were aggregated across all schools, a statistically significant association was observed between weekly absenteeism rates and WW SARS-CoV-2 with a one percent increase in the log

Indexed as

AbsenteeismCOVID-19SchoolsWastewaterChildHumansSARS-CoV-2WastewaterCOVID-19SARS-CoV-2School AbsenteeismWastewaterWastewater-Based Surveillance

Identifiers

PMID40212729
PMCPMC11981082

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.