ArticleSmall science2022
Recent Advances in Research on the Effect of Physicochemical Properties on the Cytotoxicity of Metal-Organic Frameworks.
Article in Small science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Recent Advances in Metal-Organic Framework-Based Nanozymes for Enhanced Biosensing Applications.Biosensors · 2026Review
- Toxicity Challenges and Current Advancement in Metal-Organic Frameworks (MOFs) for Biomedical Applications.Biological trace element research · 2026Review
- Importance of control experiments in toxicity test of metal-organic frameworks: Recent advances and challenges.Eco-Environment & Health · 2025Review
- Theoretical analysis of MOFs for pharmaceutical applications by using machine learning models to predict loading capacity and cell viability.Scientific reports · 2025Article
- Synthesis, Characterization, and Toxicity Evaluation of Size-Dependent Iron-Based Metal-Organic Frameworks.Nanomaterials (Basel, Switzerland) · 2025Article
- Metal-organic framework (MOF)-bioactive glass (BG) systems for biomedical applications - A review.Materials today. Bio · 2025Review
- Environmental implications of metal-organic frameworks and MXenes in biomedical applications: a perspective.RSC advances · 2023Review
- Mitigating Metal-Organic Framework (MOF) Toxicity for Biomedical Applications.Chemical engineering journal (Lausanne, Switzerland : 1996) · 2023Article
- Metal-organic frameworks functionalized biomaterials for promoting bone repair.Materials today. Bio · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metal-organic frameworks (MOFs) have been utilized with increasing interest in various fields, including gas storage and separation, catalysis, sensing, adsorption, and biomedicine. Recently, the scale-up production and commercialization of MOFs have paved their way to real-world applications. However, the accidental and intentional exposures of MOFs to humans and organisms make an increasing concern on their health risks and sustainable development. Thus, toxicity assessment is essential for the application of MOFs. In vitro toxic evaluation based on cell culture is low cost, fast, and high throughput, making it an ideal model in toxicity research. To understand the cytotoxicity of MOFs, a short review on the effect of key physicochemical factors on cytotoxicity is necessary. Herein, the application of MOFs is summarized and the possible exposure routes of MOFs to humans are discussed. Moreover, the key physicochemical factors affecting the cytotoxicity of MOFs such as chemical composition, size, and shape are also elucidated. It is expected that this short review helps to understand the cytotoxicity of MOFs and sheds light on the importance of the toxicity assessment of MOFs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.