Evidence map›Paper›PMID 40212499›Full record

ArticleJournal of orthopaedic case reports2025

Impact of Knee Pain and Osteoarthritis on Quality of Life: A Comprehensive Assessment of Physical, Social, and Psychological Factors.

Dimitrios Giotis, Maria Gianniki, Christos Koukos, Konstantia Veliou, Samundeeswari Saseendar, Alexandra Chaidou

Abstract read
In one paragraph

Article in Journal of orthopaedic case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dimitrios GiotisDepartment of Orthopaedic, General Hospital of Ioannina "G. Hatzikosta", Ioannina, Greece.
Maria GiannikiDepartment of Rheumatology, General Hospital of Ioannina "G. Hatzikosta", Ioannina, Greece.
Christos KoukosSports Trauma and Pain Institute Thessaloniki, Ploutonos, Thessaloniki, Greece.
Konstantia VeliouDepartment of Clinical Radiology, General Hospital of Ioannina "G. Hatzikosta", Ioannina, Greece.
Samundeeswari SaseendarDepartment of Orthopedic Surgery, Sri Lakshmi Narayana Institute of Medical Sciences, Puducherry, India.
Alexandra ChaidouDepartment of Clinical Radiology, General Hospital of Ioannina "G. Hatzikosta", Ioannina, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Osteoarthritis (OA) is a prevalent disease that affects the quality of life (QoL) not only through pain and physical disability but also by influencing social and psychological aspects of life. This study aims to compare patients diagnosed with knee OA to those with knee pain and other comorbidities to evaluate the specific impact of OA on QoL. Materials and Methods: A total of 150 patients presenting with knee pain or knee OA were assessed using standardized QoL instruments, including the World Health Organization QoL-BREF (WHOQOL-BREF), the Western Ontario and McMaster Universities Arthritis Index (WOMAC), the Brief Illness Perception Questionnaire (Brief IPQ), and the Patient Health Questionnaire-9 (PHQ-9). Results: The influence of various factors, such as patient characteristics, demographics, medical history, medication use, OA diagnosis, and related symptoms, was analyzed using regression models. Significant correlations were observed between QoL and variables including knee injuries (WOMAC score: 54.662 vs. 38.657, P < 0.001), depression (PHQ-9: 9.894 vs. 6.608, P < 0.001), elevated BMI (WOMAC: F = 5.305, P = 0.023), and occasional crepitus (WOMAC score: 53.144 vs. 40.175, P = 0.003). No statistically significant differences were found between patients with OA and those with other diagnoses in any of the outcome measures. Conclusions: The findings suggest that QoL is influenced more by general factors such as psychological well-being (depression), pain (knee injuries), and overall health (BMI) rather than the specific diagnosis of OA. This underscores the importance of addressing these broader health attributes to improve the QoL in patients with knee-related issues.

Indexed as

health statusKnee osteoarthritisknee painpsychological aspectsquality of life

Identifiers

PMID40212499
PMCPMC11981507

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.