Evidence map›Paper›PMID 40212400›Full record

ReviewEuropean heart journal open2025

Post-cardiac surgery atrial fibrillation and sex differences in clinical outcomes: a systematic review and meta-analysis.

Faith Michael, Travis Quevillon, Suzanne Betteridge-LeBlanc, Mustafa Alzahran, Rafael Shehata, Cynthia A Jackevicius, Rony Atoui, Bindu Bittira, Tina Baykaner, Paula Harvey and 4 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in European heart journal open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Faith MichaelDepartment of Cardiology, Health Sciences North, Northern Ontario School of Medicine University, 41 Ramsey Lake Rd, Sudbury, Ontario, Canada P3E 5J1.ORCID https://orcid.org/0000-0002-2331-4999
Travis QuevillonDepartment of Cardiology, Health Sciences North, Northern Ontario School of Medicine University, 41 Ramsey Lake Rd, Sudbury, Ontario, Canada P3E 5J1.ORCID https://orcid.org/0009-0008-5360-279X
Suzanne Betteridge-LeBlancDepartment of Cardiology, Health Sciences North, Northern Ontario School of Medicine University, 41 Ramsey Lake Rd, Sudbury, Ontario, Canada P3E 5J1.
Mustafa AlzahranDepartment of Cardiology, Health Sciences North, Northern Ontario School of Medicine University, 41 Ramsey Lake Rd, Sudbury, Ontario, Canada P3E 5J1.ORCID https://orcid.org/0009-0004-3754-6637
Rafael ShehataRoyal College of Surgeons in Ireland School of Medicine, 123 St Stephen's Green, Dublin D02 YN77, Ireland.ORCID https://orcid.org/0009-0002-7063-6218
Cynthia A JackeviciusICES, 2075 Bayview Ave, Toronto, Ontario, Canada M4N 3M5.ORCID https://orcid.org/0000-0001-5274-7251
Rony AtouiDivision of Cardiac Surgery, Health Sciences North, Northern Ontario School of Medicine University, 41 Ramsey Lake Rd, Sudbury, Ontario, Canada P3E 5J1.
Bindu BittiraDivision of Cardiac Surgery, Health Sciences North, Northern Ontario School of Medicine University, 41 Ramsey Lake Rd, Sudbury, Ontario, Canada P3E 5J1.ORCID https://orcid.org/0000-0003-4547-6670
Tina BaykanerDepartment of Medicine, Stanford University, 300 Pasteur Dr, Stanford, CA 94305, USA.
Paula HarveyWomen's College Hospital, University of Toronto, 76 Grenville St, Toronto, Ontario, Canada M5S 1B2.ORCID https://orcid.org/0000-0003-2073-1540
Ratika ParkashDivision of Cardiology, Queen Elizabeth II Health Sciences Center, Dalhousie University, 1796 Summer St, Halifax, Nova Scotia, Canada B3H 3A7.ORCID https://orcid.org/0000-0001-7630-7795
Jeff S HealeyDivision of Cardiology, Department of Medicine, McMaster University, 1200 Main St W, Hamilton, Ontario, Canada L8N 3Z5.ORCID https://orcid.org/0000-0003-1216-7580
Dennis T KoICES, 2075 Bayview Ave, Toronto, Ontario, Canada M4N 3M5.ORCID https://orcid.org/0000-0001-6840-8051
Mohammed ShurrabDepartment of Cardiology, Health Sciences North, Northern Ontario School of Medicine University, 41 Ramsey Lake Rd, Sudbury, Ontario, Canada P3E 5J1.ORCID https://orcid.org/0000-0003-2591-5111

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is conflicting literature on sex differences and clinical outcomes in patients who develop atrial fibrillation (AF) post-cardiac surgery. Our aim was to compare clinical outcomes between females and males with post-cardiac surgery AF. A systematic search was conducted for studies published until 27 September 2024 in MEDLINE, Embase, and CENTRAL. Included studies compared mortality and stroke in females vs. males who developed AF after cardiac surgery. Outcomes of interest were mortality and stroke. Pooled prevalence was used to compare comorbidities. Raw event rates were used to calculate odds ratios (ORs), which were pooled with a fixed-effects model. 10 422 studies were identified and 5 studies met inclusion criteria. 14 970 patients who developed AF after cardiac surgery were included, of whom 3748 were females. The length of follow-up was up to 10 years. The weighted average age was 70.4 ± 2.9 years in females and 66.7 ± 2.4 years in males (

Indexed as

Atrial fibrillationPost-cardiac surgerySex differences

Identifiers

PMID40212400
PMCPMC11981890

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.