Evidence map›Paper›PMID 40212284›Full record

ArticleFrontiers in genetics2025

Etiology and clinical features of Han Chinese patients with Duane retraction syndrome.

Lijuan Huang, Baoying Chen, Chi Cai, Yuyu Wu, Zhimin Sun, Yan Xie, Ningdong Li

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In one paragraph

Article in Frontiers in genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lijuan HuangDepartment of Ophthalmology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.
Baoying ChenDepartment of Ophthalmology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.
Chi CaiDepartment of CT/MRI, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.
Yuyu WuDepartment of Ophthalmology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.
Zhimin SunDepartment of Ophthalmology, Second Affiliated Hospital of Nantong University, Nantong, China.
Yan XieDepartment of Ophthalmology, Beijing Children's Hospital, Capital Medical University, Beijing, China.
Ningdong LiDepartment of Ophthalmology, The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Duane retraction syndrome (DRS) is a congenital ocular motility disorder. The aim of this study was to retrospectively describe the etiology, clinical findings, imaging characteristics, and surgical outcomes of 42 Han Chinese patients with DRS. All patients underwent detailed clinical evaluation. Next-generation sequencing was performed to identify pathogenic variants in the disease-causing genes. Magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) tractography were used to evaluate the patient's cranial nerves. Surgical procedures were designed individually to correct strabismus, abnormal facial turns, and overshooting. A total of 17 patients were diagnosed with DRS1, 4 with DRS2 and 21 with DRS3. Genetic testing revealed that two novel pathogenic variants of c.377T>C (p. Ile126Thr) and c.659A>G (p. Glu220Gly) in the

Indexed as

CHN1Duane retraction syndromeetiologySALL4treatment

Identifiers

PMID40212284
PMCPMC11983415

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