Evidence map›Paper›PMID 40212253›Full record

ArticleSmall science2024

A Glance into the Near Future: Cultivated Meat from Mammalian and Insect Cells.

Fabiana Giglio, Carmen Scieuzo, Sofia Ouazri, Valentina Pucciarelli, Dolores Ianniciello, Sophia Letcher, Rosanna Salvia, Ambrogio Laginestra, David L Kaplan, Patrizia Falabella

Abstract read
In one paragraph

Article in Small science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fabiana GiglioDepartment of Sciences University of Basilicata Via dell'Ateneo Lucano, 10 85100 Potenza Italy.ORCID https://orcid.org/0000-0003-1951-9403
Carmen ScieuzoDepartment of Sciences University of Basilicata Via dell'Ateneo Lucano, 10 85100 Potenza Italy.ORCID https://orcid.org/0000-0001-5540-0712
Sofia OuazriDepartment of Sciences University of Basilicata Via dell'Ateneo Lucano, 10 85100 Potenza Italy.ORCID https://orcid.org/0000-0002-9910-3178
Valentina PucciarelliDepartment of Sciences University of Basilicata Via dell'Ateneo Lucano, 10 85100 Potenza Italy.ORCID https://orcid.org/0000-0002-9165-133X
Dolores IannicielloDepartment of Sciences University of Basilicata Via dell'Ateneo Lucano, 10 85100 Potenza Italy.
Sophia LetcherDepartment of Biomedical Engineering School of Engineering Tufts University Colby Street, 4 Medford MA 02155 USA.ORCID https://orcid.org/0000-0003-4280-5520
Rosanna SalviaDepartment of Sciences University of Basilicata Via dell'Ateneo Lucano, 10 85100 Potenza Italy.ORCID https://orcid.org/0000-0002-6661-7164
Ambrogio LaginestraDepartment of Relations with the Territory TotalEnergies EP Italia S.P.A Via della Tecnica, 4 85100 Potenza Italy.
David L KaplanDepartment of Biomedical Engineering School of Engineering Tufts University Colby Street, 4 Medford MA 02155 USA.ORCID https://orcid.org/0000-0002-9245-7774
Patrizia FalabellaDepartment of Sciences University of Basilicata Via dell'Ateneo Lucano, 10 85100 Potenza Italy.ORCID https://orcid.org/0000-0003-0304-6867

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing global population and demand for meat have led to the need to find sustainable and viable alternatives to traditional production methods. One potential solution is cultivated meat (CM), which involves producing meat in vitro from animal stem cells to generate products with nutritional and sensory properties similar to conventional livestock-derived meat. This article examines current approaches to CM production and investigates how using insect cells could enhance the process. Cell sources are a critical issue in CM production, alongside advances in culture media, bioreactors for scalability, and scaffold development. Insect cells, compared to commonly used mammalian cells, may offer advantages in overcoming technological challenges that hinder cell culture development and expansion. The objective of this review is to emphasize how insects, as a cell source for CM production, could offer a more sustainable option. A crucial aspect for achieving this goal is a comprehensive understanding of the physiology of muscle and fat cells. In this work, the characteristics of insect and mammalian cells are compared, focusing particularly on muscle and fat cell development, regulatory pathways, hormonal regulation, and tissue composition. Insect cells are a promising source for CM, offering a sustainable and environmentally friendly alternative.

Indexed as

cellular agriculturecultivated meatinsect cell culturesscaffoldssustainable foods

Identifiers

PMID40212253
PMCPMC11935034

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.