Evidence map›Paper›PMID 40212220›Full record

ReviewAnnals of medicine and surgery (2012)2025

Antimicrobial peptides: a promising frontier to combat antibiotic resistant pathogens.

Shalini Shriwastav, Narinder Kaur, Mahmudul Hassan, Shakeel Ahmed Mohammed, Samrat Chauhan, Divya Mittal, Shahbaz Aman, Ayesha Bibi

Abstract readReview
In one paragraph

Review in Annals of medicine and surgery (2012), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Caerin 1.1/1.9 peptides controlFrontiers in microbiology · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shalini ShriwastavDepartment of Microbiology, Maharishi Markandeshwar Institute of Medical Science and Research, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, Haryana, India.
Narinder KaurDepartment of Microbiology, Maharishi Markandeshwar Institute of Medical Science and Research, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, Haryana, India.
Mahmudul HassanCenter for interdisciplinary biomedical research, Adesh University, Bhatinda, Punjab, India.
Shakeel Ahmed MohammedDepartment of Biosciences and Technology and Central Research Cell, MMEC, Maharishi Markandeshwar Deemed to be University, Mullana, Ambala, Haryana, India.
Samrat ChauhanChitkara College of Pharmacy, Chitkara University, Rajpura, Punjab, India.
Divya MittalDepartment of Biotechnology, Haryana Agriculture University, Hisar, Haryana, India.
Shahbaz AmanDepartment of Microbiology, Maharishi Markandeshwar Institute of Medical Science and Research, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala, Haryana, India.
Ayesha BibiDepartment of Pharmaceutical Technology, University of Asia Pacific, Dhaka, Bangladesh.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial peptides (AMPs) are varied naturally occurring compounds that are crucial to the innate immune system among several organisms. These peptides are effective against various bacteria, viruses, fungus, and cancer cells. Alternative therapeutic options are becoming more important as drug-resistant diseases become a global concern nowadays. AMPs unique modes of action and benefits over traditional antibiotics make them potential candidates for improving drug-resistant disease treatment. The capacity to target microbial membranes, alter intracellular processes, and bypass resistance systems distinguishes AMPs, making it challenging to develop resistance. This review examines how AMPs can combat drug-resistant bacteria and also, emphasizes on the broad-spectrum antibacterial properties of AMPs and their many mechanisms like, AMPs can permeabilize bacterial membranes, limit biofilm formation, and alter immune responses, making them promising therapeutics for infections that defy conventional treatments. As antibiotic resistance threatens global health, AMPs offer a possible path for next-generation antimicrobials.

Indexed as

antibacterial resistanceantimicrobial peptideshost defense peptidestherapeutic peptides

Identifiers

PMID40212220
PMCPMC11981355

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.