ReviewAnnals of medicine and surgery (2012)2025
Monkeypox: an in-depth examination of epidemiology, pathophysiology, and global public health implications.
Review in Annals of medicine and surgery (2012), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Serological differentiation between Mpox infection and vaccine-induced immunity: a mini-review.Frontiers in immunology · 2026Review
- The monkeypox virus suppresses autophagy by modulating Rubicon expression.Cell death discovery · 2025Article
- Mpox in people living with HIV in Brazil: spatial distribution, clinical features, and outcomes from a nationwide surveillance study.Lancet regional health. Americas · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Mpox, formerly known as monkeypox, is a zoonotic disease caused by the monkeypox virus (MPXV) within the Objectives: This narrative review aims to explore the epidemiology, transmission patterns, clinical manifestations, treatment options, and public health implications of mpox. It seeks to identify research gaps and propose strategies for prevention and management. Methodology: A comprehensive review of the literature was conducted using scientific databases and credible health organization reports. Inclusion criteria focused on studies addressing mpox epidemiology, pathophysiology, clinical presentations, and treatment strategies published up to 2024. Results: Mpox has transitioned from zoonotic origins to significant human-to-human transmission, particularly via sexual contact. Outbreaks have highlighted diverse clinical presentations, including dermatological, respiratory, and systemic symptoms, with immunocompromised individuals disproportionately affected. Tecovirimat and JYNNEOS vaccines show promise, but challenges in vaccine distribution and underreporting persist. Public health responses remain uneven, with significant disparities in low-resource settings. Conclusion: Mpox remains a pressing global health concern requiring robust surveillance, equitable vaccine access, and community-centered awareness campaigns. Research priorities include genomic studies, improved diagnostics, and targeted therapeutic approaches to mitigate future outbreaks and their socioeconomic impact.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.