ReviewAnnals of medicine and surgery (2012)2025
Surgery of craniosynostosis: a historical review.
Review in Annals of medicine and surgery (2012), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Calvarial sutures and skull-shape deformities have been recognized since ancient times, but their direct link to premature suture fusion was first established in the 19th century. The earliest surgical attempts for craniosynostosis emerged in 1890 with strip craniectomy, though early outcomes were largely unsuccessful. Surgical progress stagnated for decades due to complications and skepticism surrounding these techniques. The 20th century brought significant advancements, beginning with successful strip craniectomies in the 1920s and later attempts to prevent re-ossification through material barriers. The late 1960s marked a pivotal shift with the introduction of cranial vault remodeling, followed by the integration of external cranial vault devices and helmet therapy in the 1980s. By the 1990s, endoscopic strip craniectomy revolutionized treatment by minimizing invasiveness and blood loss. Despite these innovations, debates persist regarding optimal surgical timing, long-term outcomes, and patient adherence to treatment. Emerging technologies such as 3D imaging, artificial intelligence, and personalized medicine hold promise for the future of craniosynostosis management.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.