ReviewCurrent topics in medicinal chemistry2025
Insight into the Recent Developments of Nanoparticles in Treatment of Cancer and Neuro-Degenerative Disease: A Review.
Review in Current topics in medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCancer and neurological diseases are among the major causes of mortality and disabilities around the world. Neurological diseases are accounting for 12% of all fatalities. The major challenge in treating these diseases is the effective drug delivery to the disease site, where traditional approaches fail to give satisfactory results. As nanoparticles have many major benefits over conventional drug delivery, they have become the preferred method for drug delivery.
aimThe main objective of this review is to discuss the recent advancements and the role of nanoparticles in the effective treatment of cancer and neurodegenerative diseases.
methodsProperties of nanoparticles, such as size, shape, and surface, utilized in medical therapy showed a promising impact on the efficacy of nano-drug transportation and, as a result, therapeutic efficiency. Many potentially helpful drugs for neurological disorders cannot enter the brain in therapeutic concentrations because of the blood-brain barrier, while nanoparticles can pass through it because of their size-specific properties. Besides contributing to bioavailability and half-life, nanoparticle surface properties are also important.
resultsThe use of nanotechnology in medicine has demonstrated its importance in the field of medicine and led to the development of novel therapeutic alternatives for neurological disorders and cancer. The various types of nanoparticles, like liposomes, polymeric micelle, solid nanoparticles, quantum dots, and nanogels, have shown promising results in in-vitro models and clinical investigations.
conclusionThis review provides a concise description of the recent implications of various nanoparticles for the treatment of cancer and neurodegenerative disorders. It also helps in concise discussion of future opportunities of applications and challenges related to the production, efficacy, and safety of nanoparticles.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.