Trial reportNeurodegenerative disease management
Effect of neuromodulation on neurogenic bladder in women with multiple sclerosis: a pilot randomized controlled trial.
Trial report in Neurodegenerative disease management. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05312138 (The Effect of Different Neuromodulation Techniques in the Treatment of Multiple Sclerosis Patients With Neurogenic Bladder Dysfunction), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Different Neuromodulation Techniques in the Treatment of Multiple Sclerosis Patients With Neurogenic Bladder Dysfunction
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Non-invasive brain stimulation as a promising therapy for lower urinary tract symptoms: systematic review.World journal of urology · 2026Pooled it
- Neurogenic Pelvic Floor Dysfunctions Across Neurological Disorders: Mechanisms, Phenotypes, and Precision Rehabilitation Pathways-A Narrative Review.Journal of clinical medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimNeurogenic overactive bladder symptoms are very common in patients with multiple sclerosis (MS). In current approaches, neuromodulation methods are preferred. To investigate the effect of transcutaneous posterior tibial nerve stimulation (TPTNS) and repetitive transcranial magnetic stimulation (rTMS) on neurogenic overactive bladder symptoms in patients with MS. PATIENTS
methodsSixteen female MS patients with neurogenic overactive bladder were randomized into TPTNS and rTMS groups for a pilot study. Treatment was blinded to the investigator and statistician but not to patients and physiotherapists. Treatments were applied for a total of 10 sessions over two consecutive weeks. The primary outcome of the study was urodynamic testing, and secondary outcomes were Overactive Bladder Questionnaire-V8 (OAB-V8), Incontinence Severity Index (ISI), Incontinence Quality of Life Scale (I-QOL) and voiding diary applied before and after treatment.
resultsIn TPTNS and rTMS groups, urodynamic parameters did not show any statistically significant change within and between groups (
conclusionAlthough TPTNS and rTMS methods are not superior to each other, they can be used to reduce symptoms and improve quality of life. CLINICAL
trial registrationNCT05312138.
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Registered trials
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