Evidence map›Paper›PMID 40211765›Full record

ArticleEuropean psychiatry : the journal of the Association of European Psychiatrists2025

Sex differences in adults with attention-deficit/hyperactivity disorder: A population-based study.

Ferran Mestres, Vanesa Richarte, Juan Jesús Crespín, Carla Torrent, Santiago Biel, Carolina Ramos, Pol Ibáñez, Laura Oltra-Arañó, Montse Corrales, Silvia Amoretti and 2 more

Abstract readComparative Study
In one paragraph

Article in European psychiatry : the journal of the Association of European Psychiatrists, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
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  6. European Psychiatry: 2025 in review.European psychiatry : the journal of the Association of European Psychiatrists · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ferran MestresDepartment of Mental Health, Hospital Universitari Vall d'Hebron, Barcelona, Spain.ORCID 0009-0002-5342-4395
Vanesa RicharteDepartment of Mental Health, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Juan Jesús CrespínGroup of Psychiatry, Mental Health and Addictions, Vall d'Hebron Research Institute (VHIR), Barcelona, Spain.ORCID 0009-0007-2501-0618
Carla TorrentBiomedical Research Networking Cente for Mental Health Network (CIBERSAM), Instituto de Salud Carlos III (ISCIII), Barcelona, Spain.ORCID 0000-0003-0335-582X
Santiago BielDepartment of Mental Health, Hospital Universitari Vall d'Hebron, Barcelona, Spain.ORCID 0009-0003-1973-8400
Carolina RamosGroup of Psychiatry, Mental Health and Addictions, Vall d'Hebron Research Institute (VHIR), Barcelona, Spain.
Pol IbáñezGroup of Psychiatry, Mental Health and Addictions, Vall d'Hebron Research Institute (VHIR), Barcelona, Spain.
Laura Oltra-ArañóDepartment of Mental Health, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Montse CorralesDepartment of Mental Health, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Silvia AmorettiGroup of Psychiatry, Mental Health and Addictions, Vall d'Hebron Research Institute (VHIR), Barcelona, Spain.ORCID 0000-0001-6017-2734
Christian FadeuilheDepartment of Mental Health, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Josep Antoni Ramos-QuirogaDepartment of Mental Health, Hospital Universitari Vall d'Hebron, Barcelona, Spain.ORCID 0000-0003-1622-0350

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAttention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder that often persists into adulthood, significantly impacting daily functioning and quality of life. Sex differences influence ADHD presentation, with females experiencing delayed diagnosis and distinct patterns of severity and comorbidities. Exploring these differences is essential for improving diagnostic accuracy and developing tailored interventions. This study examines ADHD severity, psychiatric comorbidities, and functional impairment by ADHD subtype and sex.

methodsThis population-based study included 900 adults diagnosed with ADHD. ADHD severity, comorbidities, and functional outcomes were assessed using validated tools. Bivariate analyses and General Linear Models (GLMs) were applied to examine sex- and subtype-specific effects and their interactions.

resultsFemales exhibited greater ADHD severity (

conclusionsADHD presents differently across sexes and subtypes, with specific interactions influencing disability. These findings emphasize the importance of considering sex and ADHD subtype independently to enhance diagnostic accuracy and develop targeted treatment strategies.

Indexed as

AnxietyAttention Deficit Disorder with HyperactivityDepressionSex FactorsSubstance-Related DisordersAdultAge of OnsetComorbidityCost of IllnessFemaleHumansLinear ModelsMaleMiddle AgedSeverity of Illness IndexSex DistributionADHD subtypesattention-deficit/hyperactivity disorder (ADHD)functional impairmentpsychiatric comorbiditiessex differences

Identifiers

PMID40211765
PMCPMC12260720

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.