Evidence map›Paper›PMID 40211525›Full record

ArticleNeurospine2025

Loss of Mass and Surface Topography in 3-Dimensional-Printed Solid Titanium Cages Upon Impaction: An In Vitro Model.

Tien Tran, Ian M Singleton, Victor Ungurean, Andrea Rowland, Anna Martin, Oluwatodimu Richard Raji, Dimitriy G Kondrashov

Abstract read
In one paragraph

Article in Neurospine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tien TranThe Taylor Collaboration, San Francisco, CA, USA.
Ian M SingletonSan Francisco Orthopaedic Residency Program, San Francisco, CA, USA.
Victor UngureanThe Taylor Collaboration, San Francisco, CA, USA.
Andrea RowlandSan Francisco Orthopaedic Residency Program, San Francisco, CA, USA.
Anna MartinSan Francisco Orthopaedic Residency Program, San Francisco, CA, USA.
Oluwatodimu Richard RajiThe Taylor Collaboration, San Francisco, CA, USA.
Dimitriy G KondrashovSan Francisco Orthopaedic Residency Program, San Francisco, CA, USA.

Funding

Spineart
6 · The paper itself

Abstract

objectiveThere is increased use of 3-dimensional (3D)-printing for manufacturing of interbody cages to create microscale surface features that promote bone formation. Those features may be vulnerable to abrasion and/or delamination during cage impaction. Our objective was to quantify loss of mass and changes in surface topography of 3D-printed titanium interbody cages due to surgical impaction.

methodsEight surfaces of four 3D-printed titanium modular interbody fusion cages were tested. The cages were impacted into the Sawbones model with compression preload of either 200N or 400N using a guided 1-lb (0.45 kg) drop weight. Mass and surface roughness parameters of each endplate were recorded and compared for differences.

resultsSignificant weight loss was observed for the superior endplate group and for both 200N and 400N preloads. For pooled data comparison, significant postimpaction decreases were observed for mean roughness, root-mean-squared roughness, mean roughness depth, and total height of roughness profile. No significant differences were observed for profile skewness and kurtosis. There were significant changes in almost all roughness parameters in the anterior region of the cage postimpaction with significant changes in 2 out of 6 parameters in the middle, posterior, and central regions postimpaction.

conclusionThree-dimensional-printed titanium interbody fusion cages underwent loss of mass and alteration in surface topography during benchtop testing replicating physiologic conditions. There was an endplate- and region-specific postimpaction change in roughness parameters. The anterior surface experienced the largest change in surface parameters postimpaction. Our results have implications for future cage design and pre-approval testing of 3D-printed implants.

Indexed as

Anterior lumbar interbody fusionImplant designInterbody cageRoughnessSurface topographyThree-dimensional-printed titanium

Identifiers

PMID40211525
PMCPMC12010865

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.