Evidence map›Paper›PMID 40211513›Full record

ArticleNeurospine2025

Open Versus Minimally Invasive Spine Surgery in the Treatment of Single-Level Degenerative Lumbar Spondylolisthesis: An AO Spine Global Cross-Sectional Study.

Luca Ambrosio, Sathish Muthu, Samuel K Cho, Micheal S Virk, Juan P Cabrera, Patrick C Hsieh, Andreas K Demetriades, Stipe Ćorluka, S Tim Yoon, Gianluca Vadalà and 1 more

Abstract read
In one paragraph

Article in Neurospine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Luca AmbrosioOperative Research Unit of Orthopaedic and Trauma Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
Sathish MuthuDepartment of Orthopaedics, Government Medical College, Karur, India.
Samuel K ChoDepartment of Orthopaedic Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Micheal S VirkDepartment of Spine Surgery, Weill Cornell Graduate School of Medical Sciences, New York, NY, USA.
Juan P CabreraDepartment of Neurosurgery, Hospital Clínico Regional de Concepción, Concepción, Chile.
Patrick C HsiehUSC Spine Centre, Department of Neurological Surgery and Orthopaedics, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
Andreas K DemetriadesEdinburgh Spinal Surgery Outcomes Study Group, Department of Neurosurgery, Royal Infirmary, Edinburgh, UK.
Stipe ĆorlukaSpinal Surgery Division, Department of Traumatology, University Hospital Centre Sestre Milosrdnice, Zagreb, Croatia.
S Tim YoonDepartment of Orthopaedics, Emory University, Atlanta, GA, USA.
Gianluca VadalàOperative Research Unit of Orthopaedic and Trauma Surgery, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy.
AO Spine Knowledge Forum Degenerative

Funding

AO FoundationAO Spine Research Department
6 · The paper itself

Abstract

objectiveThis study aims to assess global trends in the use of open surgery versus minimally invasive surgery (MIS) for the treatment of single-level L4-5 degenerative lumbar spondylolisthesis (DLS).

methodsA cross-sectional online survey issued by the AO Spine Knowledge Forum Degenerative was conducted among AO Spine members between July and September 2023. Participants were presented with 3 clinical cases of L4-5 grade 1 DLS, each with varying degrees of stenosis and instability. The survey captured surgeon demographics and preferences for open versus MIS approaches. Statistical analysis, including chi-square tests and logistic regression, was performed to explore associations between surgical choices and surgeon demographics.

resultsA total of 943 surgeons responded, with 479 completing the survey. Open surgery was the preferred approach in all 3 cases (58.8%, 57.3%, and 42.4%, respectively), particularly in cases involving central and bilateral foraminal stenosis. MIS was the second most common choice, particularly for unilateral foraminal stenosis with mild instability (38.8%). Surgeons' preferences varied significantly by region, age, and fellowship training, with younger and fellowship-trained surgeons more likely to prefer MIS.

conclusionThe study highlights the continued predominance of open surgery for DLS, especially in complex cases, despite the growing acceptance of MIS. Significant regional and demographic variations in surgical preferences suggest the need for tailored guidelines and standardized training protocols to optimize patient outcomes. Future research should focus on the long-term efficacy of these approaches and the impact of evolving technologies on surgical decision-making.

Indexed as

FusionIndirect decompressionMinimally invasive spine surgeryOpen surgerySpondylolisthesisSurvey

Identifiers

PMID40211513
PMCPMC12010843

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.