Evidence map›Paper›PMID 40211453›Full record

ArticleMolecular and cellular biology2025

Noncoding RNA,

Meghana Matur, Yasin Uzun, Xiangguo Shi, Karina Hamamoto, Yi Qiu, Suming Huang

Abstract read
In one paragraph

Article in Molecular and cellular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Meghana MaturDivision of Pediatric Hematology/Oncology, Department of Pediatrics, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA.ORCID 0009-0009-6952-3110
Yasin UzunDivision of Pediatric Hematology/Oncology, Department of Pediatrics, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA.
Xiangguo ShiDivision of Pediatric Hematology/Oncology, Department of Pediatrics, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA.
Karina HamamotoDivision of Pediatric Hematology/Oncology, Department of Pediatrics, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA.
Yi QiuDepartment of Cellular and Molecular Physiology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA.
Suming HuangDivision of Pediatric Hematology/Oncology, Department of Pediatrics, Pennsylvania State University College of Medicine, Hershey, Pennsylvania, USA.ORCID 0000-0002-4788-2085

Funding

Role of lncRNA mediated R-loops in CTCF boundary function and AML genome organizationR01CA260729 · NCI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI Suming Huang, Mingjiang Xu · 2022 to 2026
$3.1M
Role of HOTTIP/beta-catenin-HOXA9/PRMT1 axis in hematopoietic and leukemic stem cellsR01CA264932 · NCI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI So Eric, Suming Huang · 2022 to 2026
$2.5M
Epigenetic regulation of hematopoiesisR01HL144712 · NHLBI · UNIVERSITY OF FLORIDA · PI QIU, YI · 2019 to 2022
$1.6M
Epigenetic regulation of erythropoiesisR56HL144712 · NHLBI · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI QIU, YI · 2024 to 2024
$417k
NCI NIH HHS R01 CA260729NCI NIH HHS R01 CA264932NHLBI NIH HHS R01 HL144712NHLBI NIH HHS R56 HL144712
6 · The paper itself

Abstract

Hematopoietic transcription is a combinatorial control of transcription factors, chromatin modifiers, and non-coding RNAs. TAL1 is a critical regulator of normal and malignant hematopoiesis. However, mechanism underlying regulation of TAL1 activity during erythropoiesis versus leukemogenesis remains elusive. Here, we showed that an enhancer RNA,

Indexed as

Epigenesis, GeneticErythropoiesisRNA, UntranslatedT-Cell Acute Lymphocytic Leukemia Protein 1AnimalsCell DifferentiationChromatinEnhancer Elements, GeneticHematopoietic Stem CellsHumansMicePromoter Regions, GeneticTranscription, GeneticChromatinRNA, UntranslatedTAL1 protein, humanT-Cell Acute Lymphocytic Leukemia Protein 1chromatin structureeRNAerythropoiesisgene regulationTAL1 oncogene

Identifiers

PMID40211453
PMCPMC12042867

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.