ArticleBMC public health2025
Identifying subgroups of Chinese men who have sex with men based on sexual behavior and drug use patterns using a clustering analysis approach.
Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Pleasure, shame and harm reduction: A qualitative investigation of poppers and sexualized drug use among men who have sex with men in China.The International journal on drug policy · 2026Article
- Sexualized Drug Use Linked to Higher HIV Testing Frequency Among Men Who Have Sex with Men in Three Chinese Cities with High HIV Prevalence.Substance use & misuse · 2026Article
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12 authors.
Funding
Abstract
introductionSexualized drug use (SDU) refers to using drugs before and during sex to enhance experiences, increasing high-risk behaviors, such as condomless sex, multiple sexual partners, and participation in group sex, among men who have sex with men (MSM). This study explores how SDU affects sexual behaviors in Chinese MSM.
methodsWe collected demographics, sexual acts, drug use, and condom attitudes data among 890 MSM from across China via WeChat ads through community-based organizations from March 23 to April 22, 2022.Cluster analysis using Gower's distance and hierarchical clustering explored differences in sexual acts among MSM who reported SDU in their last encounter and otherwise.
resultsCluster analysis categorized participants into three Clusters. Cluster 3 (n = 155) reported 100% SDU in their last sexual encounter (83.87% poppers use), whereas Clusters 1 (n = 581) and 2 (n = 154) reported none. Compared to other Clusters, Cluster 3 had significantly higher PrEP use (34.90% vs. 17.02% vs. 8.00%, p < 0.0001), more sexual acts over the past 12 months (35.80-61.30 vs. 31.30-56.10 and 4.37-21.22, p < 0.001), more regular (3.16 ± 4.37 vs. 2.27 ± 3.52 vs. 2.51 ± 2.53, p = 0.028) and casual partners (4.55 ± 6.55 vs. 2.48 ± 3.21 vs. 2.74 ± 3.66, p < 0.0001), more partners with STIs (8.39% vs. 3.79% vs. 3.90%, p = 0.029), and lower consistent condom use (48.53% vs. 59.41% vs. 72.28%, p < 0.0001). Cluster 1 had moderate frequency in all sexual acts except self-masturbation, which was most common in Cluster 2.
conclusionSDU is a stratum for identifying MSM subgroups, and MSM who reported SDU demonstrated higher sexual risk behaviors and PrEP usage. Among those not practicing SDU, self-masturbation is a key behavioral indicator for subgrouping.
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