Observational studyBMC oral health2025
Oral health behaviours and metabolic syndrome: mediation effect of lifestyle habits.
Observational study in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
- How dietary interventions impact oral conditions: a systematic review.BMC oral health · 2026Pooled it
- Periodontitis and Stroke Onset, Medical Costs and Length of Hospital Stay: A 5-Year Cohort Study.Journal of clinical periodontology · 2026Article
- Socioeconomic Disparities in Comorbidity of Dental Caries and Metabolic Syndrome in Norwegian Adults: A Cross-Sectional Study Using HUNT4 Survey Data.Caries research · 2026Article
- Metabolic Syndrome and Periodontitis-From Shared Mechanisms to Interdisciplinary Care: A Narrative Review of Clinical Evidence.Journal of clinical medicine · 2026Review
- Patient expectations and treatment outcomes in dentistry: A questionnaire-based study.Bioinformation · 2026Article
- ALT/AST ratio as an early marker of metabolic multimorbidity in young adults: A community-based study.Journal of multimorbidity and comorbidityArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundRecent studies have reported an association between toothbrushing frequency and systemic health. Plaque control, achieved through frequent brushing, is known to prevent dental caries and periodontal disease, potentially reducing the risk of systemic diseases. However, individuals with good oral health behaviours may also exhibit healthier lifestyle habits which could impact systemic health. In examining the relationship between oral health behaviours and systemic health, it is important to consider the influence of factors that mediate the relationship between them. This study conducted mediation analyses to evaluate the extent to which lifestyle habits and periodontal status mediate the relationship between oral health behaviours and systemic health.
methodsHealth examinations, including dental assessments, were performed on 15,579 individuals at the Aichi Health Promotion Foundation. Of these, 12,540 participants aged 40-74 years were included in the analysis. Mediation analyses were conducted using the number of metabolic syndrome (MS) components as the outcome variable, oral health behaviours (regular dental visits, use of interdental brushes or dental floss, and toothbrushing frequency) as exposure variables, lifestyle habits (smoking, drinking, exercise, and eating habits) and periodontal status as mediators, and age and sex as covariates.
resultsRegular dental visits showed significant total and indirect effects on MS, although no significant direct effect was observed. The use of interdental brushes or dental floss and toothbrushing frequency demonstrated significant total, direct and indirect effects on MS. Exercise habits, eating habits and periodontal status were significant mediators in the relationship between regular dental visits and MS. These mediators also significantly influenced the associations between both the use of interdental brushes or dental floss and toothbrushing frequency with MS.
conclusionThe relationship between oral health behaviours and MS is mediated by lifestyle habits and periodontal status. Among the mediating variables tested in this study, the indirect effects of diet and exercise habits tended to be stronger than the indirect effect of periodontal disease. Oral health behaviours may influence systemic health through their impact on lifestyle habits.
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