SynthesisBMC cancer2025
A systematic review and meta-analysis of pregnancy-associated breast cancer incidence rate.
Synthesis in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prognosis of Pregnancy-Associated Breast Cancer: A Systematic Review of Contemporary Observational Studies.Medical sciences (Basel, Switzerland) · 2026Pooled it
- Article
- Multidisciplinary management of pregnancy-associated breast cancer: a clinical pharmacy perspective on chemotherapy and perinatal outcomes.Frontiers in oncology · 2026Article
- Advances in the Treatment of Breast Cancer at Different Stages of Pregnancy.OncoTargets and therapy · 2026Review
- Pregnancy vs. Postpartum Breast Cancer: Distinct Tumor Biology and Survival Trends in a Contemporary Cohort.Cancers · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPregnancy-Associated Breast Cancer (PABC) is a special type of breast cancer that either occurs during pregnancy or one year postpartum. The aim of this systematic review and meta-analysis is to investigate the global incidence of PABC.
methodsIn this meta-analysis, to find related studies, three international databases including PubMed (Medline), Scopus and Web of Science (Clarivate analytics) were explored. An additional search was also carried out using Google Scholar in December 2023 looking for any new relevant article, and the list of references for all new supposedly relevant papers were manually searched for and investigated as well. The required data were extracted from retrieved studies and the quality of the studies was evaluated using the Newcastle-Ottawa scale checklist. Heterogeneity among studies was assessed by I-square statistic and chi-square test and due to presence of a significant heterogeneity among studies, a random-effects model was used to pool the data.
resultsTwenty-two studies were included in this meta-analysis. Among 51,944,490 number of female individuals included in the study, a total number of 7,267 cases of PABC were identified. Based on these results, the global incidence of PABC was estimated 19.2 cases per 100,000 pregnancies (95%CI: 16.1-22.2, I-square = 98.9%). The results of cumulative analysis showed that the incidence rate of PABC has risen over decades, as it increased from 13.3 cases (in 1969) to 19.2 cases (in 2022) per 100,000 pregnancies. The lowest incidence rate belonged to the American continent with 14.4 (95%CI: 9.8-19) cases per 100,000 pregnancies.
conclusionsThe results obtained from this study demonstrates that the global incidence of PABC amounts to 19.2 cases per 100,000 pregnancies and it has been increasing slowly during the last few decades as time went by. The incidence rate in developing countries seem to be higher than in the developed countries. However, more studies are required in order to reach a better conclusion on this issue.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.