Evidence map›Paper›PMID 40211220›Full record

ReviewBMC neurology2025

Autonomic dysfunction in a patient with primary headache associated with sexual activity: case report and literature review.

Yimo Zhang, Hairong Qian, Shengyuan Yu

Abstract readCase ReportsReview
PubMed Full text at PMC Publisher
In one paragraph

Review in BMC neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yimo ZhangDepartment of Neurology, Chinese PLA General Hospital, Fuxing Road 28, Beijing, CN, 100853, China.
Hairong QianDepartment of Neurology, Chinese PLA General Hospital, Fuxing Road 28, Beijing, CN, 100853, China.
Shengyuan YuDepartment of Neurology, Chinese PLA General Hospital, Fuxing Road 28, Beijing, CN, 100853, China. yusy1963@126.com.

Funding

Innovation Fostering Fund of The Sixth Medical Center of PLA General Hospital CXPY202209
6 · The paper itself

Abstract

backgroundPrimary headache associate with sexual activity (PHASA) is a relatively rare clinical condition and characterized by thunderclap headache exclusively triggered by sexual activity. The suggested involvement of autonomic dysfunction with altered cerebrovascular tone may contribute to the underlying mechanism of PHASA. However, the utilization of head-up tilt test (HUT), a valuable tool for assessing autonomic function, has not been employed in patients with PHASA. CASE PRESENTATION: We present a typical case of PHASA with positive HUT response.

conclusionAutonomic dysfunction and compensatory vasodilation due to cerebrovascular autoregulation may be part of the mechanism of PHASA.

Indexed as

Autonomic Nervous System DiseasesHeadache Disorders, PrimarySexual BehaviorFemaleHumansMiddle AgedTilt-Table TestAutonomic systemCase reportHead-up tilt testPathophysiologyPrimary headache associated with sexual activity

Identifiers

PMID40211220
PMCPMC11983823

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.