Evidence map›Paper›PMID 40211159›Full record

ArticleBMC medical research methodology2025

OpenClustered: an R package with a benchmark suite of clustered datasets for methodological evaluation and comparison.

Nathaniel Sean O'Connell, Jaime Lynn Speiser

Abstract readComparative Study
In one paragraph

Article in BMC medical research methodology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nathaniel Sean O'ConnellDepartment of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem, NC, 27157, USA.
Jaime Lynn SpeiserDepartment of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem, NC, 27157, USA. jspeiser@wakehealth.edu.

Funding

Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
CTSA UM1 Program at Wake ForestUM1TR004929 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI Jamy D Ard, KRISTIE L FOLEY · 2024 to 2026
$11.9M
Development and Validation of a Prediction Model for Longitudinal Fall Risk in Older AdultsK25AG068253 · NIA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SPEISER, JAIME LYNN · 2021 to 2025
$578k
Center for Artificial Intelligence Research at Wake Forest University School of Medicine NANational Center for Advancing Translational Sciences of the National Institutes of Health UL1TR001420National Institute On Aging of the National Institutes of Health K25AG068253NCATS NIH HHS UL1 TR001420NCATS NIH HHS UM1 TR004929NIA NIH HHS K25 AG068253
6 · The paper itself

Abstract

backgroundClustered data arise when observations are correlated within a group or sampling unit and frequently arise in epidemiology, social sciences, education, linguistics, econometrics, and medicine. Given growing interest in clustered data, we developed a data repository offering clustered datasets that can be used for methodologic comparison with open-source, publicly available data. Traditionally, data simulation studies are employed for methodology evaluation and comparison, which can be fraught with issues such as overly simplistic design and potential for bias. Excellent data repositories are available for standard (non-clustered) datasets, such as OpenML and the Penn Machine Learning Benchmark repository, but there is a paucity of resources available that have clustered data.

resultsIn this pilot study, we developed an R package called OpenClustered, which includes 19 clustered datasets with binary outcomes arising from various domains and varying in terms of their size and composition. We present tutorials for using OpenClustered, including examples for filtering and summarizing the datasets. We demonstrate the use of OpenClustered with a small benchmarking study comparing Frequentist and Bayesian implementations of generalized linear mixed models. All code and data are contained on the OpenClustered GitHub page.

conclusionThe OpenClustered R package is the start of a useful data resource for conducting benchmarking studies with open-source clustered data. It facilitates empirical methodologic guidance that is less prone to bias compared to data simulation studies, thereby improving rigor across diverse research fields. In the future, we plan to add more datasets, particularly those with continuous outcomes, as well as functionality for users to submit their clustered datasets to be included in the repository.

Indexed as

BenchmarkingDatasets as TopicSoftwareAlgorithmsBayes TheoremCluster AnalysisHumansPilot ProjectsBenchmarkingClustered dataModel evaluation

Identifiers

PMID40211159
PMCPMC11987461

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.