Evidence map›Paper›PMID 40211144›Full record

ArticleBMC neurology2025

Resveratrol attenuates the CoCl

Yamei Wang, Jian Zhao, Liang Sun, Dingding Xu, Xiaoming Wei, Jia Li, Zihan Mo, Nian Xia, Junge Zhou, Yuan Yao and 2 more

Abstract read
In one paragraph

Article in BMC neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yamei Wang *Department of Neurology, The First Affiliated Hospital of Yangtze University, Jingzhou First People's Hospital, Jingzhou, 434000, China.
Jian Zhao *Department of Neurosurgery, The First Affiliated Hospital of Yangtze University, Jingzhou First People's Hospital, Jingzhou, 434000, China.
Liang Sun *Postgraduate Training Base Alliance of WenZhou Medical University (PTBAWMU), WenZhou, 325035, Zhejiang Province, China.
Dingding XuDepartment of Neurosurgery, The First Affiliated Hospital of Yangtze University, Jingzhou First People's Hospital, Jingzhou, 434000, China.
Xiaoming WeiDepartment of Neurosurgery, The First Affiliated Hospital of Yangtze University, Jingzhou First People's Hospital, Jingzhou, 434000, China.
Jia LiSchool of clinical medicine, Yangtze University, Jingzhou, 434000, China.
Zihan MoSchool of clinical medicine, Yangtze University, Jingzhou, 434000, China.
Nian XiaSchool of clinical medicine, Yangtze University, Jingzhou, 434000, China.
Junge ZhouDepartment of Neurosurgery, General Hospital of the Yangtze River Shipping (Wuhan Brain Hospital), Wuhan, 430010, China. 43494830@qq.com.
Yuan YaoDepartment of Neurosurgery, The First Affiliated Hospital of Yangtze University, Jingzhou First People's Hospital, Jingzhou, 434000, China. 49246670@qq.com.
Qiao HuDepartment of Neurology, The First Affiliated Hospital of Yangtze University, Jingzhou First People's Hospital, Jingzhou, 434000, China. 173505051@qq.com.
Qingqing ZhouDepartment of Neurosurgery, The First Affiliated Hospital of Yangtze University, Jingzhou First People's Hospital, Jingzhou, 434000, China. 397406589@qq.com.

Funding

Jingzhou Joint Science and Technology Fund Project. 2024LHY21the Research Initiation Fund for M.D. of the First People's Hospital of Jingzhou 2023DIF10
6 · The paper itself

Abstract

backgroundStroke is a cerebrovascular disease that is the main cause of death and disability worldwide. Hypoxia is a major factor that causes neuronal damage and even cellular death. However, the mechanism and therapeutic drugs for hypoxia are not completely understood.

methodsIn this study, PC12 cells (a rat adrenal pheochromocytoma cell line) were exposed to Cobalt chloride (CoCl

resultsRES attenuated CoCl

conclusionOur results indicate that RES protects against CoCl

Indexed as

AntioxidantsCell HypoxiaCobaltLysineStilbenesAnimalsCell ProliferationCell SurvivalOxidative StressPC12 CellsRatsReactive Oxygen SpeciesResveratrolAntioxidantsCobaltcobaltous chlorideLysineReactive Oxygen SpeciesResveratrolStilbenesCoCl2HypoxiaLysine β-hydroxybutyrylationPC12 cellsReactive oxygen speciesResveratrol

Identifiers

PMID40211144
PMCPMC11984057

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.