Evidence map›Paper›PMID 40211120›Full record

ArticleBMC gastroenterology2025

Correlation and consistency analysis between various indirect portal pressure gradients and actual portal pressure gradient.

Rufeng Chen, Yaozu Liu, Li Ma, Wen Zhang, Yongjie Zhou, Minjie Yang, Jiaze Yu, Zhiping Yan, Jingqin Ma, Jianjun Luo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rufeng Chen *Shanghai Institute of Medical Imaging, Fudan University, Shanghai, China.
Yaozu Liu *Shanghai Institute of Medical Imaging, Fudan University, Shanghai, China.
Li MaShanghai Institute of Medical Imaging, Fudan University, Shanghai, China.
Wen ZhangShanghai Institute of Medical Imaging, Fudan University, Shanghai, China.
Yongjie ZhouShanghai Institute of Medical Imaging, Fudan University, Shanghai, China.
Minjie YangShanghai Institute of Medical Imaging, Fudan University, Shanghai, China.
Jiaze YuShanghai Institute of Medical Imaging, Fudan University, Shanghai, China.
Zhiping YanShanghai Institute of Medical Imaging, Fudan University, Shanghai, China.
Jingqin Ma *Shanghai Institute of Medical Imaging, Fudan University, Shanghai, China.
Jianjun Luo *Shanghai Institute of Medical Imaging, Fudan University, Shanghai, China. luo.jianjun@zs-hospital.sh.cn.

Funding

clinical research special fund from Zhongshan Hospital, Fudan University 2018ZSLC23Device development exploration project from National Clinical Research Center for Interventional Medicine 2021-001Excellent youth program from Zhongshan Hospital, Fudan University (2019ZSYXQN38)National Natural Science Foundation of China 82302323Shanghai key clinical specialty construction program W2019028
6 · The paper itself

Abstract

objectiveTo evaluate the correlation and consistency between hepatic venous pressure gradient(F-HVPG) calculated as the wedged hepatic venous pressure (WHVP) minus free hepatic venous pressure (FHVP), I-HVPG calculated as WHVP minus inferior vena cava pressure (IVCP) in the hepatic segment, and portal pressure gradient (PPG).

methodsData were collected from 112 patients with portal hypertension undergoing transjugular intrahepatic portosystemic shunt (TIPS) along with HVPG measurement. FHVP, IVCP, WHVP, and portal venous pressure (PVP) were collected intraoperatively. Pearson's correlation and Bland-Altman method were used to assess correlation and consistency.

resultsA total of 112 patients were retrospectively collected. The correlation coefficient (r) values (p < 0.001) between FHVP and IVCP, WHVP and PVP, F-HVPG and I-HVPG, F-HVPG and PPG, I-HVPG and PPG were 0.835, 0.717, 0.946, 0.667 and 0.698, respectively; the determination coefficient (R

conclusionF-HVPG and I-HVPG demonstrated high correlation and consistency. I-HVPG consistently correlates more closely with PPG than F-HVPG, both in the overall cohort and in patients with FHVP-IVCP > 2 mmHg. These results suggest that I-HVPG may serve as a more reliable alternative. Due to the significant underestimation of the PPG, HVPG measurement should not be used to exclude patients from a TIPS intervention.

Indexed as

Hypertension, PortalPortal PressureAdultAgedCorrelation of DataFemaleHepatic VeinsHumansMaleMiddle AgedPortasystemic Shunt, Transjugular IntrahepaticRetrospective StudiesVena Cava, InferiorHepatic venous pressure gradientInferior vena cava pressurePortal hypertensionPortal pressure gradientTransjugular intrahepatic portosystemic shunt (TIPS)

Identifiers

PMID40211120
PMCPMC11987172

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.