Evidence map›Paper›PMID 40211056›Full record

ArticleEuropean journal of sport science2025

Quantifying Leg Muscle Disuse Atrophy During Bed Rest Using DXA, CT, and MRI.

Cas J Fuchs, Wesley J H Hermans, Job van den Hurk, Christopher J Wiggins, Per Widholm, Olof Dahlqvist Leinhard, Pandichelvam Veeraiah, Joachim E Wildberger, Jeanine J Prompers, Luc J C van Loon

Abstract read
In one paragraph

Article in European journal of sport science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Cas J FuchsDepartment of Human Biology, NUTRIM Institute of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, the Netherlands.
Wesley J H HermansDepartment of Human Biology, NUTRIM Institute of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, the Netherlands.
Job van den HurkScannexus Ultra High-Field MRI Center, Maastricht, the Netherlands.
Christopher J WigginsScannexus Ultra High-Field MRI Center, Maastricht, the Netherlands.
Per WidholmAMRA Medical AB, Linköping, Sweden.
Olof Dahlqvist LeinhardAMRA Medical AB, Linköping, Sweden.
Pandichelvam VeeraiahScannexus Ultra High-Field MRI Center, Maastricht, the Netherlands.
Joachim E WildbergerDepartment of Radiology and Nuclear Medicine, School for Cardiovascular Diseases (CARIM), Maastricht University Medical Centre+, Maastricht, the Netherlands.
Jeanine J PrompersDepartment of Human Biology, NUTRIM Institute of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, the Netherlands.
Luc J C van LoonDepartment of Human Biology, NUTRIM Institute of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, the Netherlands.

Funding

Stimuleringsfonds FHML
6 · The paper itself

Abstract

This study evaluated whether dual-energy X-ray absorptiometry (DXA), computed tomography (CT), and magnetic resonance imaging (MRI) provide comparable outcomes in quantifying disuse-induced skeletal muscle atrophy. Although the calculation of muscle volume using MRI analysis may be considered the gold standard, the method remains labor intense and, as such, less practical and more costly. In this context, we also evaluated the efficacy of a commercially available automated MRI analysis method to measure changes in leg muscle volume after two weeks of bed rest. Twelve healthy, male adults (age: 24 ± 3 years, BMI: 23.7 ± 3.1 kg/m

Indexed as

Absorptiometry, PhotonBed RestLegMagnetic Resonance ImagingMuscle, SkeletalMuscular AtrophyMuscular Disorders, AtrophicTomography, X-Ray ComputedAdultHumansMaleYoung Adultcomputed tomographydual‐energy x‐ray absorptiometrymagnetic resonance imagingmuscle massmuscle volumeskeletal muscle

Identifiers

PMID40211056
PMCPMC11985322

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.