ArticleEye (London, England)2025
Childhood or adolescent abuse and primary open-angle glaucoma in a longitudinal cohort of women.
Article in Eye (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Investigation of Optic Nerve Sheath Diameter, Intraocular Pressure, and Dry Eye in Patients with Borderline Personality Disorder: The Role of Childhood Trauma.Journal of clinical medicine · 2025Article
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Authors and funding
7 authors.
Funding
Abstract
objectiveTo examine associations of childhood/adolescence abuse with primary open-angle glaucoma (POAG) and POAG subtypes.
methodsWe included US female nurse participants from the Nurses' Health Study II (1989-2019). Participants (n = 59,712) were ≥40 years old, reported follow-up eye exams, had no glaucoma, and had early-life adverse experience data. Self-reported childhood/adolescence abuse was assessed in 2001 with the Revised Conflict Tactics Scale (CTS) and the 2-item sexual maltreatment scale of the parent-child CTS. We evaluated associations by type (any, physical, sexual) and timing (childhood, adolescence). POAG cases (n = 255) were confirmed and subtyped with medical record review. Multivariable-adjusted Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs).
resultsSevere childhood/adolescent abuse was reported by 16.5%. There was no association between any childhood/adolescent abuse (HR 1.03; 95% CI: 0.79-1.35), physical abuse, abuse experienced during childhood only or adolescence only, and POAG risk. Compared to no sexual abuse history, any sexual abuse was modestly associated with POAG (HR 1.31; 95% CI: 1.01-1.69). Specifically, we observed adverse associations with sexual abuse for the POAG subtype with paracentral vs. peripheral VF loss (P
conclusionsWhile any childhood/adolescence abuse history was not associated with POAG, the modest adverse associations with early-life sexual abuse history warrant confirmation in future studies.
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