Evidence map›Paper›PMID 40211005›Full record

ArticleNature methods2025

Pooled CRISPR screening with optical sequencing reveals regulators of 3D chromatin organization.

Mazhar Adli

Abstract read
In one paragraph

Article in Nature methods, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Mazhar AdliFeinberg School of Medicine at Northwestern University, Robert H. Lurie Comprehensive Cancer Center, Department of Obstetrics and Gynecology, Chicago, IL, USA. adli@northwestern.edu.ORCID http://orcid.org/0000-0003-4740-9594

Funding

Technology Development UnitU54CA268084 · NCI · NORTHWESTERN UNIVERSITY · PI Vadim Backman, Daniela E Matei · 2022 to 2026
$10.0M
Molecular and cellular characterization of essential human genes.UM1HG012649 · NHGRI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Mazhar Adli, Paul W. Burridge · 2022 to 2026
$8.1M
Chemo-mediated transcriptional reprogramming in ovarian cancerR01CA267544 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI ADLI, MAZHAR · 2022 to 2025
$2.2M
Identifying the Drivers and Targeting Chemo Resistance in Ovarian CancerR01CA211648 · NCI · UNIVERSITY OF VIRGINIA · PI ADLI, MAZHAR · 2017 to 2021
$2.1M
NCI NIH HHS R01 CA211648NCI NIH HHS R01 CA267544NCI NIH HHS U54 CA268084NHGRI NIH HHS UM1 HG012649
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40211005
PMCPMC12089732

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.