ArticleScientific reports2025
Diagnostic reference level, achievable dose, and effective dose estimation in adult hybrid SPECT myocardial perfusion imaging in Institut Jantung Negara.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
This study aims to establish the diagnostic reference level (DRL), achievable dose (AD), and effective dose (ED) estimation for adult hybrid SPECT myocardial perfusion imaging (MPI) procedures at Institut Jantung Negara (IJN). 737 subjects referred for MPI studies from January to June 2024 were included in the analysis. These subjects underwent either a one-day or two-day Tc-99 m tetrofosmin protocol using a cardiac-dedicated single-photon emission computed tomography (SPECT), either GE SPECT Discovery NM530c or GE SPECT Ventri. All subjects also underwent a cardiac CT scan via an external positron emission tomography/computed tomography (PET/CT) system, GE Discovery MI Digital Ready for either CT attenuation correction (CTAC) or CT coronary artery calcium score (CAC) protocol, depending on their clinical condition. The one-day protocol showed AD of 240.50 MBq and 691.90 MBq for the first and second injections, respectively, with corresponding DRL of 263.63 MBq and 777.93 MBq. The two-day protocol involved higher ADs of 1106.30 MBq and 1073.00 MBq for the first and second injections, with DRL of 1239.50 MBq and 1221.00 MBq, respectively. In the CTAC protocol, the AD for CT dose index volume (CTDI
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