Evidence map›Paper›PMID 40210855›Full record

ArticleScientific data2025

Haplotype-resolved genomes of Trichophyton mentagrophytes and Trichophyton tonsurans.

Sijie Feng, Zhenhui Wang, Kainan Lin, Kun Wang, Shuting Zheng, Qianqian Wang, Lianyu Lin, Yunkun Lu

Abstract readDataset
In one paragraph

Article in Scientific data, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sijie Feng *School of Medicine, Henan Polytechnic University, 454000, Jiaozuo, China.
Zhenhui Wang *School of Medicine, Henan Polytechnic University, 454000, Jiaozuo, China.
Kainan Lin *School of Medicine, Zhejiang University, 310016, Hangzhou, China.
Kun WangSchool of Medicine, Henan Polytechnic University, 454000, Jiaozuo, China.
Shuting ZhengSchool of Medicine, Henan Polytechnic University, 454000, Jiaozuo, China.
Qianqian WangSchool of Medicine, Zhejiang University, 310016, Hangzhou, China. wangqian_cc@zju.edu.cn.
Lianyu LinState Key Laboratory of Ecological Pest Control for Fujian and Taiwan Crops, College of Life Science, Fujian Agriculture and Forestry University, 350002, Fuzhou, China. lianyulin.bio@gmail.com.
Yunkun LuSchool of Medicine, Zhejiang University, 310016, Hangzhou, China. kevenloo1@zju.edu.cn.ORCID http://orcid.org/0000-0001-7605-1259

Funding

National Natural Science Foundation of China (National Science Foundation of China) No. 82403083National Natural Science Foundation of China (National Science Foundation of China) No. 82403160
6 · The paper itself

Abstract

Dermatophytes have posed a significant health concern due to their ability to parasitize human and animal skin, hair, and nails, causing a spectrum of dermatological conditions. However, the absence of high-quality genomes hinders our understanding of the dermatophytes. In this study, we utilized the circular consensus sequencing (CCS) technology to generate haplotype-resolved, nearly-complete genomes for two representative dermatophytes, Trichophyton mentagrophytes and Trichophyton tonsurans. Total sizes of the genomes ranged from 23.8 Mb to 25.2 Mb, with the contig N50 lengths of 6.47 Mb and 12.65 Mb, respectively. Each genome assembly was gapless and possessed three pseudochromosomes, with two achieving telomere-to-telomere (T2T) level. BUSCO analysis of the assemblies revealed approximately 99% of genome completeness. More than 7500 protein-coding genes were identified, and over 99% of the genes were well annotated through multiple gene function databases. Approximately 10% of the genomes were covered by repeats, particularly retrotransposons. Our findings provided valuable genomic resources of dermatophytes, paving the way for developing more effective medical interventions and public health strategies against Trichophyton infections.

Indexed as

ArthrodermataceaeGenome, FungalHaplotypesTrichophytonHumans

Identifiers

PMID40210855
PMCPMC11985949

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.