Evidence map›Paper›PMID 40210848›Full record

ArticleNature communications2025

The overlapping global distribution of dengue, chikungunya, Zika and yellow fever.

Ahyoung Lim, Freya M Shearer, Kara Sewalk, David M Pigott, Joseph Clarke, Azhar Ghouse, Ciara Judge, Hyolim Kang, Jane P Messina, Moritz U G Kraemer and 12 more

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Evaluation of the NovaplexInternational journal of molecular sciences · 2026
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  7. A Review on Ylang-Ylang (Molecules (Basel, Switzerland) · 2026
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Alignment-freeJournal of clinical microbiology · 2026
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Ahyoung LimDepartment of Infectious Disease Epidemiology and Dynamics, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK.ORCID http://orcid.org/0000-0003-4445-5034
Freya M ShearerInfectious Disease Dynamics Unit, Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia.
Kara SewalkBoston Children's Hospital, Boston, MA, USA.
David M PigottInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-6731-4034
Joseph ClarkeUniversity of Cambridge, Cambridge, UK.ORCID http://orcid.org/0009-0002-2466-9932
Azhar GhouseDepartment of Infectious Disease Epidemiology and Dynamics, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK.
Ciara JudgeDepartment of Infectious Disease Epidemiology and Dynamics, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK.ORCID http://orcid.org/0000-0001-7923-9898
Hyolim KangDepartment of Infectious Disease Epidemiology and Dynamics, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK.
Jane P MessinaSchool of Geography and the Environment, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0001-7829-1272
Moritz U G KraemerDepartment of Biology, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0001-8838-7147
Katy A M GaythorpeMRC Centre for Global Infectious Disease Analysis, School of Public Health, Imperial College London, London, UK.ORCID http://orcid.org/0000-0003-3734-9081
William M de SouzaDepartment of Microbiology, Immunology and Molecular Genetics, University of Kentucky, College of Medicine, Lexington, KY, USA.
Elaine O NsoesieDepartment of Global Health, School of Public Health, Boston University, Boston, MA, USA.ORCID http://orcid.org/0000-0001-9170-8714
Michael CeloneInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
Nuno FariaVirus Genomic Epidemiology, Faculty of Medicine, School of Public Health, Imperial College, London, Imperial College London, London, UK.ORCID http://orcid.org/0000-0001-8839-2798
Sadie J RyanDepartment of Geography and the Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA.ORCID http://orcid.org/0000-0002-4308-6321
Ingrid B RabeDepartment of Epidemic and Pandemic Preparedness and Prevention, World Health Organization, Geneva, Switzerland.
Diana P RojasDepartment of Epidemic and Pandemic Preparedness and Prevention, World Health Organization, Geneva, Switzerland.
Simon I HayInstitute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-0611-7272
John S BrownsteinDepartment of Pediatrics, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0001-8568-5317
Nick GoldingInfectious Disease Dynamics Unit, Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia.ORCID http://orcid.org/0000-0001-8916-5570
Oliver J BradyDepartment of Infectious Disease Epidemiology and Dynamics, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, UK. Oliver.Brady@lshtm.ac.uk.ORCID http://orcid.org/0000-0002-3235-2129

Funding

Gates Foundation INV-009125RCUK | Medical Research Council (MRC) MR/V031112/1Wellcome TrustWorld Health Organization 001
6 · The paper itself

Abstract

Arboviruses transmitted mainly by Aedes (Stegomyia) aegypti and Ae. albopictus, including dengue, chikungunya, and Zika viruses, and yellow fever virus in urban settings, pose an escalating global threat. Existing risk maps, often hampered by surveillance biases, may underestimate or misrepresent the true distribution of these diseases and do not incorporate epidemiological similarities despite shared vector species. We address this by generating new global environmental suitability maps for Aedes-borne arboviruses using a multi-disease ecological niche model with a nested surveillance model fit to a dataset of over 21,000 occurrence points. This reveals a convergence in suitability around a common global distribution with recent spread of chikungunya and Zika closely aligning with areas suitable for dengue. We estimate that 5.66 (95% confidence interval 5.64-5.68) billion people live in areas suitable for dengue, chikungunya and Zika and 1.54 (1.53-1.54) billion people for yellow fever. We find large national and subnational differences in surveillance capabilities with higher income more accessible areas more likely to detect, diagnose and report viral diseases, which may have led to overestimation of risk in the United States and Europe. When combined with estimates of uncertainty, these suitability maps can be used by ministries of health to target limited surveillance and intervention resources in new strategies against these emerging threats.

Indexed as

Chikungunya FeverDengueYellow FeverZika Virus InfectionAedesAnimalsChikungunya virusGlobal HealthHumansMosquito VectorsYellow fever virusZika Virus

Identifiers

PMID40210848
PMCPMC11986131

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.