ArticleMolecular biology reports2025
Over-expression of Tfgd2-RsAFP2 fusion gene isolated from fenugreek and radish shows enhanced disease resistance against Alternaria blight disease caused by Alternaria alternata in transgenic pigeonpea.
Article in Molecular biology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Selective α-Amylase Inhibition by Plant Defensins: Structural Determinants, Engineering Strategies, and Translational Prospects.Probiotics and antimicrobial proteins · 2026Review
- Editorial: Molecular mechanisms of plant responses to pathogens and pests in a changing climate.Molecular biology reports · 2026Article
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Abstract
backgroundPigeonpea is the second-most significant legume crop grown in tropics and subtropics. A substantial global concern lowering the yields of important crops like pigeonpea is disease-related damage which is accounting for major crop loss. Pigeonpea infestation with numerous insect pests and diseases result in reduced productivity. Among these Alternaria blight disease caused by Alternaria alternata fungi is one among the factors leading to decreased productivity. At micro-molar concentrations, fungal and bacterial growth can be inhibited by plant defensins, which are short, basic peptides rich in cysteine. METHODS AND
resultsIn the present investigation, two defensins Tfgd2 (Trigonella foenum-graecum defensin 2) and RsAFP2 (Raphanus sativus antifungal protein 2) combined by a linker peptide was incorporated as a fusion gene into pigeonpea through Agrobacterium mediated transformation. T
conclusionOur findings illustrate the promising activity of Tfgd2-RsAFP2 fusion gene in conferring Alternaria blight disease resistance in transgenic pigeonpea and the same can be employed in the further development of disease resistant transgenic lines in pigeonpea improvement studies.
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